Klinisk utprøving av larynksmaske sammenlignet med ansiktsmaske ved gjenopplivning av nyfødte i lavinntektsland

Face mask ventilation (FMV) is the most common method of resuscitating neonates in poor settings. It is mostly performed by midwives but may not always be satisfactory. The i-gel® is a cuffless supraglottic airway which is easy to insert and provides an efficient seal that prevents air leakage with the potential to enhance the performance of neonatal resuscitation. OBJECTIVE To investigate whether the use of a cuffless supraglottic airway compared to face-mask ventilation during neonatal resuscitation can reduce mortality at 7 days, morbidity in neonatal encephalopathy (NE) in asphyxiated neonates. TRIAL A multi-centre phase III, randomized clinical trial will be conducted in Mozambique and Uganda, among asphyxiated neonates in the delivery units. Resuscitation will be performed according to international guidelines. UTILITY It is crucial to explore alternative, cost-effective modalities that not only would reduce mortality, but also the burden of neurological damage in survivors.