Cristin-prosjekt-ID: 415844
Sist endret: 9. januar 2015 15:55
Cristin-prosjekt-ID: 415844
Sist endret: 9. januar 2015 15:55
Prosjekt

Exploitation of high-density genetic marker maps in modern fish breeding programmes

prosjektleder

Theodorus Meuwissen
ved Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

prosjekteier / koordinerende forskningsansvarlig enhet

  • NOFIMA
  • Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

Finansiering

  • Norges forskningsråd

Klassifisering

Vitenskapsdisipliner

Genetikk og genomikk • Husdyravl, oppdrett, forplantning

Emneord

Fisk

Tidsramme

Avsluttet
Start: 1. oktober 2004 Slutt: 30. november 2007

Beskrivelse Beskrivelse

Tittel

Exploitation of high-density genetic marker maps in modern fish breeding programmes

Sammendrag

Del av Forskningsrådsprosjekt ledet fra Akvaforsk. Norwegian and foreign genomics and comparative mapping projects will soon identify thousands of genes in several fish species, as well as polymorphisms within all these genes. The competitive advantage for Norwegian fish breeding depends however not on being the first to develop this knowledge, but being the first to effectively make use of this information. This project aims at cashing in on all this technological opportunity for fish breeding. We will develop methodology that predicts total genetic value using high-density marker information. The methodology will predict additive and dominance effects of individual chromosome segments, which are identified by closely linked markers, and which will make direct selection at the DNA level possible. Optimal combinations of chromosome segments can be predicted and selected for using this information. The prediction of total genetic value will be extended towards predicting these effects for several traits simultaneously in order to facilitate the selection for complex breeding goals. The methodology will be tested in computer simulations. The implementation of this novel method of selecting at the DNA level in generic fish breeding programs will be optimized. NFR 159831

Vitenskapelig sammendrag

Del av Forskningsrådsprosjekt ledet fra Akvaforsk. Norwegian and foreign genomics and comparative mapping projects will soon identify thousands of genes in several fish species, as well as polymorphisms within all these genes. The competitive advantage for Norwegian fish breeding depends however not on being the first to develop this knowledge, but being the first to effectively make use of this information. This project aims at cashing in on all this technological opportunity for fish breeding. We will develop methodology that predicts total genetic value using high-density marker information. The methodology will predict additive and dominance effects of individual chromosome segments, which are identified by closely linked markers, and which will make direct selection at the DNA level possible. Optimal combinations of chromosome segments can be predicted and selected for using this information. The prediction of total genetic value will be extended towards predicting these effects for several traits simultaneously in order to facilitate the selection for complex breeding goals. The methodology will be tested in computer simulations. The implementation of this novel method of selecting at the DNA level in generic fish breeding programs will be optimized. NFR 159831

Tittel

Exploitation of high-density genetic marker maps in modern fish breeding programmes

Sammendrag

Del av Forskningsrådsprosjekt ledet fra Akvaforsk. Norwegian and foreign genomics and comparative mapping projects will soon identify thousands of genes in several fish species, as well as polymorphisms within all these genes. The competitive advantage for Norwegian fish breeding depends however not on being the first to develop this knowledge, but being the first to effectively make use of this information. This project aims at cashing in on all this technological opportunity for fish breeding. We will develop methodology that predicts total genetic value using high-density marker information. The methodology will predict additive and dominance effects of individual chromosome segments, which are identified by closely linked markers, and which will make direct selection at the DNA level possible. Optimal combinations of chromosome segments can be predicted and selected for using this information. The prediction of total genetic value will be extended towards predicting these effects for several traits simultaneously in order to facilitate the selection for complex breeding goals. The methodology will be tested in computer simulations. The implementation of this novel method of selecting at the DNA level in generic fish breeding programs will be optimized.

Vitenskapelig sammendrag

Del av Forskningsrådsprosjekt ledet fra Akvaforsk. Norwegian and foreign genomics and comparative mapping projects will soon identify thousands of genes in several fish species, as well as polymorphisms within all these genes. The competitive advantage for Norwegian fish breeding depends however not on being the first to develop this knowledge, but being the first to effectively make use of this information. This project aims at cashing in on all this technological opportunity for fish breeding. We will develop methodology that predicts total genetic value using high-density marker information. The methodology will predict additive and dominance effects of individual chromosome segments, which are identified by closely linked markers, and which will make direct selection at the DNA level possible. Optimal combinations of chromosome segments can be predicted and selected for using this information. The prediction of total genetic value will be extended towards predicting these effects for several traits simultaneously in order to facilitate the selection for complex breeding goals. The methodology will be tested in computer simulations. The implementation of this novel method of selecting at the DNA level in generic fish breeding programs will be optimized.

prosjektdeltakere

prosjektleder

Theodorus Meuwissen

  • Tilknyttet:
    Prosjektleder
    ved Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

Anna Sonesson

  • Tilknyttet:
    Prosjektdeltaker
    ved NOFIMA

Trygve Roger Solberg

  • Tilknyttet:
    Prosjektdeltaker
    ved Andre divisjoner ved NOFIMA
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