Cristin-prosjekt-ID: 415921
Sist endret: 17. januar 2014 12:51
Cristin-prosjekt-ID: 415921
Sist endret: 17. januar 2014 12:51
Prosjekt

Functional genomics for optimized milk and meat quality

prosjektleder

Sigbjørn Lien
ved Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

prosjekteier / koordinerende forskningsansvarlig enhet

  • Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

Finansiering

  • Norges forskningsråd

Klassifisering

Vitenskapsdisipliner

Husdyravl, oppdrett, forplantning • Bioteknologi

Emneord

Genomikk • Melk • Kjøtt • Ernæring • Dyrehelse • Fenotype

Tidsramme

Avsluttet
Start: 1. juli 2006 Slutt: 30. september 2009

Beskrivelse Beskrivelse

Tittel

Functional genomics for optimized milk and meat quality

Sammendrag

Summary: The present proposal is one of several coordinated projects intended to ensure a comprehensive genome-wide marker-description of the Norwegian cattle population and its diversity. The bovine genome sequence will be published in 2006. Norway has one of the world's best databases on the genetic history, productivity and health of individual cows and bulls. Together, these resources offer dramatically new tools for understanding and improving important aspects of animal health, production economy, milk and meat healthiness and consumer acceptability. TINE uses an advanced and extensive quality control system for milk based on Ff-IR spectroscopy, generating millions of informative, multi-channel measurements of milk per year. This project will try to extract much more information from these milk measurements by calibrating them for a number of new phenotypes, such as fatty acid profile, animal energy balance etc. This information will then be split mathematically into genetic and environmental and feeding contributions, both of which can be used directly within existing breeding- and farm-¬advice schemes. Another ongoing project (NFR-156740/I10) concerns tenderness and intramuscular fat in young NRF bulls, and this new project will reanalyse these data in order to search for more aspects of tenderness variations. Three other projects (NFR-I60871/S10, NFR-159136/S10 and EU-PL 01625-2-SABRE) provide funding to genotype a set of 25K genome wide distributed SNPs in a large number of progeny tested NRF bulls. In this project we will use the 25K chip in a genome search for genes affecting meat quality by doing selective genotyping of 380 bulls from the project NFR-156740/I10. New statistical tools will compress these, in light of pedigree information, into haplotypes - stable" gene packages" that correlate to phenotypes such as productivity, milk protein, fatty acid profile, animal nutrition and health, beef tenderness etc. Interesting genes will be pursued by new techniques within transcriptomics, proteomics and biospectroscopy at Campus Ås in an interdisciplinary effort. NFR 173321

Vitenskapelig sammendrag

Summary: The present proposal is one of several coordinated projects intended to ensure a comprehensive genome-wide marker-description of the Norwegian cattle population and its diversity. The bovine genome sequence will be published in 2006. Norway has one of the world's best databases on the genetic history, productivity and health of individual cows and bulls. Together, these resources offer dramatically new tools for understanding and improving important aspects of animal health, production economy, milk and meat healthiness and consumer acceptability. TINE uses an advanced and extensive quality control system for milk based on Ff-IR spectroscopy, generating millions of informative, multi-channel measurements of milk per year. This project will try to extract much more information from these milk measurements by calibrating them for a number of new phenotypes, such as fatty acid profile, animal energy balance etc. This information will then be split mathematically into genetic and environmental and feeding contributions, both of which can be used directly within existing breeding- and farm-¬advice schemes. Another ongoing project (NFR-156740/I10) concerns tenderness and intramuscular fat in young NRF bulls, and this new project will reanalyse these data in order to search for more aspects of tenderness variations. Three other projects (NFR-I60871/S10, NFR-159136/S10 and EU-PL 01625-2-SABRE) provide funding to genotype a set of 25K genome wide distributed SNPs in a large number of progeny tested NRF bulls. In this project we will use the 25K chip in a genome search for genes affecting meat quality by doing selective genotyping of 380 bulls from the project NFR-156740/I10. New statistical tools will compress these, in light of pedigree information, into haplotypes - stable" gene packages" that correlate to phenotypes such as productivity, milk protein, fatty acid profile, animal nutrition and health, beef tenderness etc. Interesting genes will be pursued by new techniques within transcriptomics, proteomics and biospectroscopy at Campus Ås in an interdisciplinary effort. NFR 173321

prosjektdeltakere

prosjektleder

Sigbjørn Lien

  • Tilknyttet:
    Prosjektleder
    ved Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet

Theodorus Meuwissen

  • Tilknyttet:
    Prosjektdeltaker
    ved Institutt for husdyr- og akvakulturvitenskap ved Norges miljø- og biovitenskapelige universitet
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Resultater Resultater

Functional genomics and biospectroscopy for optimized milk and meat quality.

Lien, Sigbjørn; Kohler, Achim; Wold, Jens-Petter; Afseth, Nils Kristian; Martens, Harald; Aass, Laila; Jørgensen, Knut; Selmer-Olsen, Eirik. 2006, The International Skjervold-symposium 2006. NMBU, TINE, NOFIMAPoster
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