Cristin-prosjekt-ID: 547375
Registrert av: REK Sist endret: 10. august 2017 00:00 Sist endret av: REK

Cristin-prosjekt-ID: 547375
Registrert av: REK Sist endret: 10. august 2017 00:00 Sist endret av: REK
Prosjekt

Reliability of Free and Total BPA analyte measures in MoBa

prosjektleder

Heidi Aase
ved Folkehelseinstituttet

prosjekteier / koordinerende forskningsansvarlig enhet

  • Folkehelseinstituttet

Godkjenninger

  • Regionale komitéer for medisinsk og helsefaglig forskningsetikk (REK) - 2011/1386

Kategorier

Helseprosjekttype

Annet studium

Tidsramme

Avsluttet
Start: 1. august 2011 Slutt: 31. desember 2014

Beskrivelse Beskrivelse

Tittel

Reliability of Free and Total BPA analyte measures in MoBa

Populærvitenskapelig sammendrag

BBPA is rapidly metabolized. Therefore in the absence of a constant exposure source and intensity, biomarker levels would be expected to change over time, as has previously been reported. Only free (unconjugated) BPA exhibits endocrine activity*** however, in general, existing epidemiological studies have measured total BPA (the sum of free and conjugated) biomarkers. Total BPA biomarker concentration may further be impacted by contamination with environmental sources of free BPA, or in the biospecimen collection process or materials. We propose a reliability study of BPA biomarkers over the course of pregnancy that separates total and free BPA, using the reliability substudy urine samples collected in MoBa.

Tittel

Reliability of Free and Total BPA analyte measures in MoBa

Populærvitenskapelig sammendrag

BBPA is rapidly metabolized. Therefore in the absence of a constant exposure source and intensity, biomarker levels would be expected to change over time, as has previously been reported. Only free (unconjugated) BPA exhibits endocrine activity*** however, in general, existing epidemiological studies have measured total BPA (the sum of free and conjugated) biomarkers. Total BPA biomarker concentration may further be impacted by contamination with environmental sources of free BPA, or in the biospecimen collection process or materials. We propose a reliability study of BPA biomarkers over the course of pregnancy that separates total and free BPA, using the reliability substudy urine samples collected in MoBa.

prosjektdeltakere

prosjektleder

Heidi Aase

  • Tilknyttet:
    Prosjektleder
    ved Folkehelseinstituttet
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