Cristin-resultat-ID: 1233047
Sist endret: 28. november 2017 10:56
NVI-rapporteringsår: 2015
Resultat
Vitenskapelig artikkel
2015

Irisin in Blood Increases Transiently after Single Sessions of Intense Endurance Exercise and Heavy Strength Training

Bidragsytere:
  • Håvard Nygård
  • Gunnar Slettaløkken
  • Geir Vegge
  • Ivana Hollan
  • Jon Elling Whist
  • Tor Strand
  • mfl.

Tidsskrift

PLOS ONE
ISSN 1932-6203
e-ISSN 1932-6203
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2015
Volum: 10
Hefte: 3
Open Access

Importkilder

Scopus-ID: 2-s2.0-84924956462

Beskrivelse Beskrivelse

Tittel

Irisin in Blood Increases Transiently after Single Sessions of Intense Endurance Exercise and Heavy Strength Training

Sammendrag

Purpose Irisin is a recently identified exercise-induced hormone that increases energy expenditure, at least in rodents. The main purpose of this study was to test the hypothesis that Irisin increases acutely in blood after singular sessions of intense endurance exercise (END) and heavy strength training (STR). Secondary, we wanted to explore the relationship between body composition and exercise-induced effects on irisin, and the effect of END and STR on muscular expression of the irisin gene FNDC5. Methods Nine moderately trained healthy subjects performed three test days using a randomized and standardized crossover design: one day with 60 minutes of END, one day with 60 minutes of STR, and one day without exercise (CON). Venous blood was sampled over a period of 24h on the exercise days. Results Both END and STR led to transient increases in irisin concentrations in blood, peaking immediately after END and one hour after STR, before gradually returning to baseline. Irisin responses to STR, but not END, showed a consistently strong negative correlation with proportions of lean body mass. Neither END nor STR affected expression of FNDC5, measured 4h after training sessions, though both protocols led to pronounced increases in PGC-1α expression, which is involved in transcriptional control of FNDC5. Conclusion The results strongly suggest that single sessions of intense endurance exercise and heavy strength training lead to transient increases in irisin concentrations in blood. This was not accompanied by increased FNDC5 expression, measured 4h post-exercise. The results suggest that irisin responses to resistance exercise are higher in individuals with lower proportions of lean body mass.

Bidragsytere

Aktiv cristin-person

Håvard Nygård

  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet

Gunnar Slettaløkken Falch

Bidragsyterens navn vises på dette resultatet som Gunnar Slettaløkken
  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet
Aktiv cristin-person

Geir Vegge

  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet

Ivana Hollan

  • Tilknyttet:
    Forfatter
    ved Revmatismesykehuset AS

Jon Elling Whist

  • Tilknyttet:
    Forfatter
    ved Div Medisinsk service ved Sykehuset Innlandet HF
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