Cristin-resultat-ID: 1324350
Sist endret: 8. mars 2017, 23:59
NVI-rapporteringsår: 2015
Resultat
Vitenskapelig artikkel
2016

Development of a disease-specific health-related quality of life (HRQoL) questionnaire intended to be used in conjunction with the general European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) in renal cell carcinoma patients

Bidragsytere:
  • Elisabeth Grov Beisland
  • Hans Jørgen Aarstad
  • Anne Kari Hersvik Aarstad
  • August Bakke
  • Leif Bostad og
  • Christian Beisland

Tidsskrift

Acta Oncologica
ISSN 0284-186X
e-ISSN 1651-226X
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2016
Publisert online: 2015
Trykket: 2016
Volum: 55
Hefte: 3
Sider: 349 - 356

Importkilder

Scopus-ID: 2-s2.0-84938830408

Beskrivelse Beskrivelse

Tittel

Development of a disease-specific health-related quality of life (HRQoL) questionnaire intended to be used in conjunction with the general European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) in renal cell carcinoma patients

Sammendrag

Abstract Introduction: Studying Health-Related Quality of Life (HRQoL) following cancer treatment has become part of a growing number of standardized treatment protocols. The European Organization for Research and Treatment of Cancer (EORTC) has developed HRQoL questionnaires aimed at cancer patients. A disease-specific part is not available for renal cell carcinoma (RCC) patients, and the present aim was to develop an EORTC-compatible RCC-specific HRQoL questionnaire. Material and methods: Four-hundred-and-thirteen RCC patients were treated with radical or partial nephrectomies in Western Norway during the period from 1997-2010. Three-hundred-and-nine patients with histologically proven cancer were still alive at the inclusion time point. One-hundred-and-eighty-five RCC patients (71% response rate) returned the questionnaires. We determined HRQoL by the EORTC-QLQ C30 questionnaire. We also asked 13 candidates questions aimed at constituting a disease-specific part. Furthermore, we tested parts of personality by the Eysenck Personality Inventory and coping by the COPE questionnaire. Given tumor treatment, TNM stage, alcohol consumption level and smoking levels were also determined from the hospital records. Results: A factor analysis showed that five factors were formed: one general symptomatic, one general functional, one with disease-specific questions (flank pain, blood in the urine, flank edema, urinary tract infection), one about sexuality and one about weight loss or gain. Ten RCC-specific HRQoL questions were derived from a factor analysis, including four questions related particularly to pain, mobility and social functioning, also representing a short version of the EORTC C30. The psychometric properties and the relation to other psychological and clinical variables were further determined to be satisfactory. Conclusions: The suggested disease-specific EORTC-QLQ-style RCC10 version adds important information about the HRQoL of RCC patients, providing additional apparent value to the general questionnaire and personality variables, as well as being psychometrically satisfactory. The questionnaire has a potential as a “stand alone” HRQoL questionnaire among RCC patients. Keywords: factor analysis, disease-specific questionnaire, Health-Related Quality of Life, RCC patients  

Bidragsytere

Elisabeth Grov Beisland

  • Tilknyttet:
    Forfatter
    ved Institutt for helse- og omsorgsvitskap ved Høgskulen på Vestlandet
  • Tilknyttet:
    Forfatter
    ved Klinisk institutt 1 ved Universitetet i Bergen

Hans Jørgen Aarstad

  • Tilknyttet:
    Forfatter
    ved Klinisk institutt 1 ved Universitetet i Bergen
  • Tilknyttet:
    Forfatter
    ved Klinikk for hode/hals ved Helse Bergen HF - Haukeland universitetssykehus

Anne Kari Hersvik Aarstad

  • Tilknyttet:
    Forfatter
    ved Klinikk for hode/hals ved Helse Bergen HF - Haukeland universitetssykehus
  • Tilknyttet:
    Forfatter
    ved Fakultet for helsefag ved VID vitenskapelige høgskole

August Bakke

  • Tilknyttet:
    Forfatter
    ved Kirurgisk klinikk ved Helse Bergen HF - Haukeland universitetssykehus
  • Tilknyttet:
    Forfatter
    ved Klinisk institutt 1 ved Universitetet i Bergen

Leif Bostad

  • Tilknyttet:
    Forfatter
    ved Avdeling for patologi ved Helse Bergen HF - Haukeland universitetssykehus
  • Tilknyttet:
    Forfatter
    ved Klinisk institutt 1 ved Universitetet i Bergen
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