Cristin-resultat-ID: 1405368
Sist endret: 3. februar 2017, 15:33
NVI-rapporteringsår: 2016
Resultat
Vitenskapelig artikkel
2016

The association between hair cortisol and self-reported symptoms of depression in pregnant women

Bidragsytere:
  • Ellen Wikenius
  • Vibeke Moe
  • Marian Kjellevold Malde
  • Lars Smith
  • Robert Lyle
  • Rune Waagbø
  • mfl.

Tidsskrift

PLOS ONE
ISSN 1932-6203
e-ISSN 1932-6203
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2016
Volum: 11
Hefte: 9
Open Access

Importkilder

Scopus-ID: 2-s2.0-84991237138

Beskrivelse Beskrivelse

Tittel

The association between hair cortisol and self-reported symptoms of depression in pregnant women

Sammendrag

Depression has been linked to an imbalance in cortisol. Until recently, cortisol has been studied by measuring concentrations at single time points in blood or saliva samples. Cortisol concentrations vary with circadian rhythm and experiences, from time point to time point. The measurement of hair cortisol concentration (HCC) is a new method of accessing mean, long-term cortisol concentrations. Recent studies show positive associations between depression and HCC, and prenatal maternal cortisol is thought to influence the developing fetus. We therefore examined the association between HCC and self-reported symptoms of depression in second trimester pregnant women. Participants were 181 women, recruited between September 2011 and October 2013 to the Little-in-Norway (LiN)-study. These women answered the Edinburgh Postnatal Depression Rating Scale (EPDS) on self-reported symptoms of depression, and one cm maternal scalp hair was collected and analyzed for cortisol concentrations. Multiple regression analyses did not show depressive symptoms as a predictor for HCC in our selection of pregnant women, while gestational age was significantly related. In conclusion, our study indicated that symptoms of depression during pregnancy did not predict HCC, but further studies of clinically depressed, pregnant women using gestational age as an adjustment variable are warranted.

Bidragsytere

Ellen Wikenius

  • Tilknyttet:
    Forfatter
    ved Enhet barne- og ungdomspsykiatri ved Universitetet i Oslo

Vibeke Moe

  • Tilknyttet:
    Forfatter
    ved RBUP Øst og Sør
  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo

Marian Kjellevold

Bidragsyterens navn vises på dette resultatet som Marian Kjellevold Malde
  • Tilknyttet:
    Forfatter
    ved Sjømat og ernæring ved Havforskningsinstituttet

Lars Smith

  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo

Robert Lyle

  • Tilknyttet:
    Forfatter
    ved Seksjon for galenisk farmasi og samfunns ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Avdeling for medisinsk genetikk ved Oslo universitetssykehus HF
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