Cristin-resultat-ID: 1420543
Sist endret: 4. januar 2017 10:20

Medication review in patients with mental disabilities.

  • Anne Gerd Granås
  • Amani Qasem Mohammed
  • Julie Aanensen
  • Kjell H. Halvorsen og
  • Cecilie Johannessen Landmark


Navn på arrangementet: 45th ESCP Symposium on Clinical Pharmacy
Dato fra: 5. oktober 2016
Dato til: 7. oktober 2016


Arrangørnavn: European Society of Clinical Pharmacy

Om resultatet

Publiseringsår: 2016

Beskrivelse Beskrivelse


Medication review in patients with mental disabilities.


Background and Objective: Systematic medication reviews in interdisciplinary teams can help to identify potential and actual drug-related problems (DRP). The Centre for Development of Institutional and Home Care Services in Oslo, Norway, conducted medication reviews for polypharmacy patients with mental disabilities in 2015-2016, based on a lack of knowledge about drug-related problems in this patient group. The objective was to examine prescribing patterns, frequencies and types of DRP in patients with mental disabilities. Setting and Method: The forms for medication reviews were developed by the national patient safety campaign in Norway. The nurse/social educator recruited eligible patients, observed them, and ordered test if needed. The clinical pharmacist (JWA) reviewed the medications to identify DRPs. The interdisciplinary case conference took place at the different general practitioners’ offices being responsible for the individual patients. The general practitioner, the nurse/social educator and the pharmacist were present, and in some cases, also patients took part. Main outcome measures: An independent researcher (AQM) collected and analysed the data based on the DRP-forms containing information on the prescribed medicines, strength, dose, indication, a description of DRP and suggested interventions to resolve them. Results: Overall, 40 patients with mental disabilities, aged 34-77 years, consented to have a medication review. They used on average 12 medicines (range 5-23). The team identified 191 DRP in 39 of the 40 patients (average 4.9, range 0-13). Overall, 79 % of all DRP were resolved. For one-third of the medicines, an action was taken to improve the prescribing. The most commonly medicines were analgesics (62 %), antiepileptics (58 %) and anxiolytics (52 %). The most frequent DRPs were unnecessary drug choice (24 %), side effects (11 %) and too low dose (11 %). DRPs were most common in antipsychotics (10 %), antidepressants (9 %) and anxiolytics (7 %). Conclusion: Patients with intellectual disabilities take more medicines and have many DRPs compared to other patient groups. They are also more prone to taking combinations of CNS-active medicines and therefore more at risk of side effects and drug interactions.


Anne Gerd Granås

  • Tilknyttet:
    ved Galenisk farmasi og samfunnsfarmasi ved Universitetet i Oslo

Amani Qasem Mohammed

  • Tilknyttet:
    ved Institutt for naturvitenskapelige helsefag ved OsloMet - storbyuniversitetet

Julie Aanensen

  • Tilknyttet:

Kjell H. Halvorsen

  • Tilknyttet:
    ved Klinisk farmasi og farmakoepidemiologi, forskningsgruppe ved UiT Norges arktiske universitet

Cecilie Johannessen Landmark

  • Tilknyttet:
    ved Farmasøytisk institutt ved Universitetet i Oslo
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