Cristin-resultat-ID: 1463769
Sist endret: 1. juni 2017, 14:52
NVI-rapporteringsår: 2017
Resultat
Vitenskapelig artikkel
2017

The cost-effectiveness of cervical self-sampling to improve routine cervical cancer screening: The importance of respondent screening history and compliance

Bidragsytere:
  • Emily Burger
  • Stephen Sy
  • Mari Nygård og
  • Jane J Kim

Tidsskrift

Cancer Epidemiology, Biomarkers and Prevention
ISSN 1055-9965
e-ISSN 1538-7755
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2017
Volum: 26
Hefte: 1
Sider: 95 - 103

Importkilder

Scopus-ID: 2-s2.0-85009062966

Beskrivelse Beskrivelse

Tittel

The cost-effectiveness of cervical self-sampling to improve routine cervical cancer screening: The importance of respondent screening history and compliance

Sammendrag

Background: Human papillomavirus (HPV) testing allows women to self-collect cervico-vaginal cells at home (i.e., self-sampling). Using primary data from a randomized pilot study, we evaluated the long-term consequences and cost-effectiveness of using self-sampling to improve participation to routine cervical cancer screening in Norway. Methods: We compared a strategy reflecting screening participation (using reminder letters) to strategies that involved mailing self-sampling device kits to women non-compliant to screening within a 5-year or 10-year period under two scenarios: A) self-sampling respondents had moderate under-screening histories, or B) respondents to self-sampling had moderate and severe under-screening histories. Model outcomes included quality-adjusted life-years (QALY) and lifetime costs. The 'most cost-effective' strategy was identified as the strategy just below $100,000 per QALY gained. Results: Mailing self-sampling device kits to all women non-compliant to screening within a 5-year or 10-year period can be more effective and less costly than the current reminder letter policy; however, the optimal self-sampling strategy was dependent on the profile of self-sampling respondents. For example, '10-yearly self-sampling' is preferred ($95,500 per QALY gained) if '5-yearly self-sampling' could only attract moderate under-screeners; however, '5-yearly self-sampling' is preferred if this strategy could additionally attract severe under-screeners. Conclusions: Targeted self-sampling of non-compliers likely represents good value-for-money; however, the preferred strategy is contingent on the screening histories and compliance of respondents. Impact: The magnitude of the health benefit and optimal self-sampling strategy is dependent on the profile and behavior of respondents. Health authorities should understand these factors prior to selecting and implementing a self-sampling policy.

Bidragsytere

Aktiv cristin-person

Emily Annika Burger

Bidragsyterens navn vises på dette resultatet som Emily Burger
  • Tilknyttet:
    Forfatter
    ved Harvard School of Public Health
  • Tilknyttet:
    Forfatter
    ved Helseledelse og helseøkonomi ved Universitetet i Oslo

Stephen Sy

  • Tilknyttet:
    Forfatter
    ved Harvard School of Public Health

Mari Nygård

  • Tilknyttet:
    Forfatter
    ved Kreftregisteret - Institutt for populasjonsbasert kreftforskning

Jane J Kim

  • Tilknyttet:
    Forfatter
    ved Harvard School of Public Health
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