Cristin-resultat-ID: 1464311
Sist endret: 6. februar 2018, 10:43
NVI-rapporteringsår: 2017
Resultat
Vitenskapelig artikkel
2017

Acute effects of post-absorptive and postprandial moderate exercise on markers of inflammation in hyperglycemic individuals

Bidragsytere:
  • Håvard Nygård
  • Gunnar Slettaløkken
  • Jon Elling Whist
  • Ivana Hollan
  • Stian Ellefsen
  • Gerd Holmboe-Ottesen
  • mfl.

Tidsskrift

European Journal of Applied Physiology
ISSN 1439-6319
e-ISSN 1439-6327
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2017
Volum: 117
Hefte: 4
Sider: 1 - 8
Open Access

Importkilder

Scopus-ID: 2-s2.0-85014067487

Beskrivelse Beskrivelse

Tittel

Acute effects of post-absorptive and postprandial moderate exercise on markers of inflammation in hyperglycemic individuals

Sammendrag

Abstract Purpose Systemic inflammation is involved in the development of several diseases, including cardiovascular disease and type 2 diabetes. It is known that vigorous exercise affects systemic inflammation, but less is known about exercise at lower intensities. Hyperglycemia can also entail pro-inflammatory responses; however, postprandial hyperglycemia is blunted if the meal is followed by exercise. Hypotheses were: (1) moderate physical exercise acutely affects levels of C-reactive protein (CRP) and serum soluble vascular cell adhesion molecule 1 (sVCAM-1) in hyperglycemic individuals and (2) the effect depends on whether the activity is performed in a post-absorptive or postprandial state. Methods Twelve participants diagnosed with hyperglycemia, but not using anti-diabetic medication, underwent three test days in a randomized cross-over study; 1 control day without exercise, 1 day with 60 min of treadmill walking ending 30 min before breakfast, and 1 day with an identical bout of activity 30 min after the start of breakfast. Food intake was strictly standardized and venous blood for CRP, and sVCAM-1 analysis was sampled at standardized timepoints during the first 3.5 h after breakfast and once 24 h later. Results Merged data from the two exercise days showed that sVCAM-1 increased from baseline (4 ± 16 ng/mL) compared to the control condition (−28 ± 47 ng/mL, ES = 0.7, p = 0.024). There was no statistically significant difference in changes in sVCAM-1 levels between the two exercise test days. Exercise did not affect CRP values. Conclusion Moderate exercise increases sVCAM-1 in hyperglycemic individuals, whereas it does not affect CRP.

Bidragsytere

Aktiv cristin-person

Håvard Nygård

  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet

Gunnar Slettaløkken Falch

Bidragsyterens navn vises på dette resultatet som Gunnar Slettaløkken
  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet

Jon Elling Whist

  • Tilknyttet:
    Forfatter
    ved Avd Forskning ved Sykehuset Innlandet HF
  • Tilknyttet:
    Forfatter
    ved Div Medisinsk service ved Sykehuset Innlandet HF

Ivana Hollan

  • Tilknyttet:
    Forfatter
    ved Brigham and Women's Hospital
  • Tilknyttet:
    Forfatter
    ved Avd Forskning ved Sykehuset Innlandet HF
  • Tilknyttet:
    Forfatter
    ved Harvard Medical School
  • Tilknyttet:
    Forfatter
    ved Revmatismesykehuset AS
Aktiv cristin-person

Stian Ellefsen

  • Tilknyttet:
    Forfatter
    ved Institutt for folkehelse- og idrettsvitenskap ved Høgskolen i Innlandet
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