Cristin-resultat-ID: 1465206
Sist endret: 26. oktober 2017 18:58
NVI-rapporteringsår: 2017
Resultat
Vitenskapelig artikkel
2017

Type 2 diabetes and comorbid symptoms of depression and anxiety: Longitudinal associations with mortality risk

Bidragsytere:
  • Kiyuri Naicker
  • Jeffrey A. Johnson
  • Jens Christoffer Skogen
  • Douglas Manuel
  • Simon Nygaard Øverland
  • Børge Sivertsen
  • mfl.

Tidsskrift

Diabetes Care
ISSN 0149-5992
e-ISSN 1935-5548
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2017
Volum: 40
Hefte: 3
Sider: 352 - 358

Importkilder

Scopus-ID: 2-s2.0-85019688638

Beskrivelse Beskrivelse

Tittel

Type 2 diabetes and comorbid symptoms of depression and anxiety: Longitudinal associations with mortality risk

Sammendrag

OBJECTIVE Depression is strongly linked to increased mortality in individuals with type 2 diabetes. Despite high rates of co-occurring anxiety and depression, the risk of death associated with comorbid anxiety in individuals with type 2 diabetes is poorly understood. This study documented the excess mortality risk associated with symptoms of depression and/or anxiety comorbid with type 2 diabetes. RESEARCH DESIGN AND METHODS Using data for 64,177 Norwegian adults from the second wave of the NordTrondelag Health Study (HUNT2), with linkage to the Norwegian Causes of Death Registry, we assessed all-cause mortality from survey participation in 1995 through to 2013. We used Cox proportional hazards models to examine mortality risk over 18 years associated with type 2 diabetes status and the presence of comorbid affective symptoms at baseline. RESULTS Three clear patterns emerged from our findings. First, mortality risk in individuals with diabetes increased in the presence of depression or anxiety, or both. Second, mortality risk was lowest for symptoms of anxiety, higher for comorbid depression- anxiety, and highest for depression. Lastly, excess mortality risk associated with depression and anxiety was observed in men with diabetes but not in women. The highest risk of death was observed in men with diabetes and symptoms of depression only (hazard ratio 3.47, 95% CI 1.96, 6.14). CONCLUSIONS This study provides evidence that symptoms of anxiety affect mortality risk in individuals with type 2 diabetes independently of symptoms of depression, in addition to attenuating the relationship between depressive symptoms and mortality in these individuals.

Bidragsytere

Kiyuri Naicker

  • Tilknyttet:
    Forfatter
    ved University of Ottawa

Jeffrey A. Johnson

  • Tilknyttet:
    Forfatter
    ved University of Alberta

Jens Christoffer Skogen

  • Tilknyttet:
    Forfatter
    ved Avdeling for helsefremmende arbeid ved Folkehelseinstituttet
  • Tilknyttet:
    Forfatter
    ved Regionalt kompetansesenter for rusforskning ved Helse Stavanger HF - Stavanger universitetssjukehus

Douglas Manuel

  • Tilknyttet:
    Forfatter
    ved University of Ottawa

Simon Nygaard Øverland

  • Tilknyttet:
    Forfatter
    ved Institutt for samfunnspsykologi ved Universitetet i Bergen
  • Tilknyttet:
    Forfatter
    ved Psykisk og fysisk helse ved Folkehelseinstituttet
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