Cristin-resultat-ID: 1475424
Sist endret: 19. mars 2018 16:07
NVI-rapporteringsår: 2017
Resultat
Vitenskapelig artikkel
2017

Incidence and prevalence of childhood epilepsy: A nationwide cohort study

Bidragsytere:
  • Kari Modalsli Aaberg
  • Nina Gunnes
  • Inger Johanne Bakken
  • Camilla Lund Søraas
  • Alexander Berntsen
  • Per Magnus
  • mfl.

Tidsskrift

Pediatrics
ISSN 0031-4005
e-ISSN 1098-4275
NVI-nivå 2

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2017
Volum: 139
Hefte: 5
Artikkelnummer: e20163908

Importkilder

Scopus-ID: 2-s2.0-85019025220

Beskrivelse Beskrivelse

Tittel

Incidence and prevalence of childhood epilepsy: A nationwide cohort study

Sammendrag

BACKGROUND AND OBJECTIVES: Epilepsy affects 0.5% to 1% of children and is the most frequent chronic neurologic condition in childhood. Incidence rates appear to be declining in high-income countries. The validity of epilepsy diagnoses from different data sources varies, and contemporary population-based incidence studies are needed. METHODS: The study was based on the Norwegian Mother and Child Cohort Study. Potential epilepsy cases were identified through registry linkages and parental questionnaires. Cases were validated through medical record reviews and telephone interviews of parents. RESULTS: The study population included 112 744 children aged 3 to 13 years (mean 7.4 years) at end of registry follow-up (December 31, 2012). Of these, 896 had registry recordings and/or questionnaire reports of epilepsy. After validation, 587 (66%) met the criteria for an epilepsy diagnosis. The incidence rate of epilepsy was 144 per 100 000 person-years in the first year of life and 58 per 100 000 for ages 1 to 10 years. The cumulative incidence of epilepsy was 0.66% at age 10 years, with 0.62% having active epilepsy. The 309 children (34%) with erroneous reports of epilepsy from the registry and/or the questionnaires had mostly been evaluated for nonepileptic paroxysmal events, or they had undergone electroencephalography examinations because of other developmental or neurocognitive difficulties. CONCLUSIONS: Approximately 1 out of 150 children is diagnosed with epilepsy during the first 10 years of life, with the highest incidence rate observed during infancy. Validation of epilepsy diagnoses in administrative data and cohort studies is crucial because reported diagnoses may not meet diagnostic criteria for epilepsy.

Bidragsytere

Kari Modalsli Aaberg

  • Tilknyttet:
    Forfatter
    ved Folkehelseinstituttet
  • Tilknyttet:
    Forfatter
    ved Spesialsykehus for epilepsi (SSE) ved Oslo universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Avdeling for kompleks epilepsi ved Universitetet i Oslo

Nina Gunnes

  • Tilknyttet:
    Forfatter
    ved Avdeling for barns helse og utvikling ved Folkehelseinstituttet

Inger Johanne Landsjøåsen Bakken

Bidragsyterens navn vises på dette resultatet som Inger Johanne Bakken
  • Tilknyttet:
    Forfatter
    ved Avdeling for barns helse og utvikling ved Folkehelseinstituttet

Camilla Lund Søraas

  • Tilknyttet:
    Forfatter
    ved Folkehelseinstituttet

Alexander Berntsen

  • Tilknyttet:
    Forfatter
    ved Barne- og ungdomsklinikken ved Akershus universitetssykehus HF
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