Cristin-resultat-ID: 1534407
Sist endret: 26. februar 2019 13:59
NVI-rapporteringsår: 2017
Resultat
Vitenskapelig artikkel
2018

Association of Maternal Psychosocial Stress with Increased Risk of Asthma Development in Offspring

Bidragsytere:
  • Maria Christine Magnus
  • Rosalind J. Wright
  • Espen Røysamb
  • Christine Louise Parr
  • Øystein Karlstad
  • Christian Page
  • mfl.

Tidsskrift

American Journal of Epidemiology
ISSN 0002-9262
e-ISSN 1476-6256
NVI-nivå 2

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2018
Publisert online: 2017
Volum: 187
Hefte: 6
Sider: 1199 - 1209

Importkilder

Scopus-ID: 2-s2.0-85049001069

Finansiering

  • Norges forskningsråd
    Prosjektkode: 221097
  • Norges forskningsråd
    Prosjektkode: 262700

Beskrivelse Beskrivelse

Tittel

Association of Maternal Psychosocial Stress with Increased Risk of Asthma Development in Offspring

Sammendrag

Prenatal maternal psychosocial stress might influence childhood asthma development. Evaluating paternal psychosocial stress and conducting a sibling comparison could provide further insight into the role of unmeasured confounding. We examined the associations of parental psychosocial stress during and after pregnancy with asthma at 7 years in the Norwegian Mother and Child Cohort Study (n = 63,626). Measures of psychosocial stress included lifetime major depressive symptoms, current anxiety/depression symptoms, use of antidepressants, anxiolytics and/or hypnotics, life satisfaction, relationship satisfaction, work stress and social support. Childhood asthma was associated with maternal lifetime major depressive symptoms, adjusted relative risk (aRR) = 1.19 (95% CI: 1.09, 1.30), in addition to symptoms of anxiety/depression during pregnancy, aRR = 1.17 (95% CI: 1.06, 1.29), and 6 months after delivery, aRR = 1.17 (95% CI: 1.07, 1.28). Maternal negative life events during pregnancy, aRR = 1.10 (95% CI: 1.06, 1.13), and 6 months after delivery, aRR = 1.14 (95% CI: 1.11, 1.18), were also associated with asthma. These associations were not replicated when evaluated within sibling groups. There were no associations with paternal psychosocial stress. In conclusion, maternal anxiety/depression and negative life events was associated with offspring asthma, but this might be explained by unmeasured maternal background characteristics that remain stable across deliveries.

Bidragsytere

Maria Christine Magnus

  • Tilknyttet:
    Forfatter
    ved Avdeling for kroniske sykdommer og aldring ved Folkehelseinstituttet
  • Tilknyttet:
    Forfatter
    ved University of Bristol

Rosalind J. Wright

  • Tilknyttet:
    Forfatter
    ved Mount Sinai School of Medicine of the City University of New York
Aktiv cristin-person

Espen Røysamb

  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Avdeling for barns helse og utvikling ved Folkehelseinstituttet

Christine Louise Parr

  • Tilknyttet:
    Forfatter
    ved Folkehelseinstituttet

Øystein Karlstad

  • Tilknyttet:
    Forfatter
    ved Avdeling for kroniske sykdommer og aldring ved Folkehelseinstituttet
1 - 5 av 10 | Neste | Siste »