Cristin-resultat-ID: 1577563
Sist endret: 6. august 2018 10:27
NVI-rapporteringsår: 2018
Resultat
Vitenskapelig artikkel
2018

Dissatisfaction with opioid maintenance treatment partly explains reported side effects of medications

Bidragsytere:
  • Ashley Elizabeth Muller
  • Ronny Bjørnestad og
  • Thomas Clausen

Tidsskrift

Drug and Alcohol Dependence
ISSN 0376-8716
e-ISSN 1879-0046
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2018
Publisert online: 2018
Trykket: 2018
Volum: 187
Sider: 22 - 28

Importkilder

Scopus-ID: 2-s2.0-85044945883

Klassifisering

Vitenskapsdisipliner

Andre klinisk medisinske fag

Emneord

Rusmidler, misbruk/behandling • Brukermedvirkning • Tilfredshet • Beboermedvirkning

HRCS

  • Helsekategori: 10 - Mental helse
    Aktivitet: 6.6 - Psykologiske og atferdsmessige
  • Helsekategori: 10 - Mental helse
    Aktivitet: 6.1 - Legemidler

Beskrivelse Beskrivelse

Tittel

Dissatisfaction with opioid maintenance treatment partly explains reported side effects of medications

Sammendrag

Background Drop-out is a core problem in opioid maintenance treatment (OMT), but patients’ reactions to and acceptance of the various OMT medications are insufficiently investigated. In Norway, there has been vocal patient resistance to the newest medication, buprenorphine-naloxone (BNX), and complaints have focused on the side effect profile. There has been no comparison of patient satisfaction and side effects of the three most common OMT medications. Aim To compare patient satisfaction with OMT and side effects of BNX, buprenorphine monopreparate (BUP), and methadone (MET) as reported by patients. Methods Data were drawn from a national peer-to-peer survey developed by a patient advocacy group. The survey engaged more than 1000 OMT patients, corresponding to one seventh of OMT patients in Norway. The associations between side effects, treatment satisfaction, and patient characteristics were tested in multinomial logistic regressions. Results High patient satisfaction with OMT overall was reported despite lower satisfaction with medication itself and widely prevalent side effects. Among each medication group, dissatisfaction with medications or OMT in general along with poor health status increased the relative risk ratio of reporting the heaviest side effect burden. MET users reported the highest side effect burden and BNX users the lightest, but BNX users were more dissatisfied with their medication. Conclusions Side effects are a concern for nearly all OMT patients, and they do not appear to accumulate with age or length of treatment. BNX users’ dissatisfaction with their medication is of particular concern, and expectations and preferences of medication may be influencing their dissatisfaction.

Bidragsytere

Ashley Elizabeth Muller

  • Tilknyttet:
    Forfatter
    ved Senter for rus- og avhengighetsforskning ved Universitetet i Oslo

Ronny Bjørnestad

  • Tilknyttet:
    Forfatter
    ved Diverse norske bedrifter og organisasjoner

Thomas Clausen

  • Tilknyttet:
    Forfatter
    ved Senter for rus- og avhengighetsforskning ved Universitetet i Oslo
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