Cristin-resultat-ID: 1580916
Sist endret: 20. mars 2019 10:28
NVI-rapporteringsår: 2018
Resultat
Vitenskapelig artikkel
2018

Telemonitoring in chronic obstructive pulmonary disease (chromed) a randomized clinical trial

Bidragsytere:
  • Paul P. Walker
  • Pasquale Pompilio
  • Paolo Zanaboni
  • Trine Strand Bergmo
  • Kaiu Prikk
  • Andrei Malinovschi
  • mfl.

Tidsskrift

American Journal of Respiratory and Critical Care Medicine
ISSN 1073-449X
e-ISSN 1535-4970
NVI-nivå 2

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2018
Publisert online: 2018
Volum: 198
Hefte: 5
Sider: 620 - 628

Importkilder

Scopus-ID: 2-s2.0-85052708097

Beskrivelse Beskrivelse

Tittel

Telemonitoring in chronic obstructive pulmonary disease (chromed) a randomized clinical trial

Sammendrag

Rationale: Early detection of COPD exacerbations using tele-monitoring of physiological variables might reduce the frequency of hospitalisation. Objectives: To evaluate the efficacy of home monitoring of lung mechanics by the forced oscillation technique (FOT) and cardiac parameters in older COPD patients with co-morbidities. Methods: This multicentre, randomized clinical trial recruited 312 GOLD grade II-IV COPD patients (median age 71 years [IQR:66-76], 49.6% grade II, 50.4% grade III-IV), with a history of exacerbation in the previous year and at least one non-pulmonary co-morbidity. Patients were randomised to usual care (n=158) or tele-monitoring (n=154) and followed for 9 months. All tele-monitoring patients self-assessed lung mechanics daily and in a subgroup with congestive heart failure (n=37) cardiac parameters were also monitored. An algorithm identified deterioration, triggering a telephone contact to determine appropriate interventions. Measurements and Main results: Primary outcomes were time to first hospitalisation (TTFH) and change in EQ-5D utility index score. Secondary outcomes included: rate of antibiotic/corticosteroid prescriptions, hospitalisation, CAT, PHQ-9 and MLHF questionnaire scores, quality-adjusted life years and healthcare costs. Tele-monitoring did not affect TTFH, EQ-5D utility index score, antibiotic prescriptions, hospitalization rate and questionnaire scores. In an exploratory analysis, tele-medicine was associated with fewer repeat hospitalizations (-54%, p=0.017). Conclusions: In older COPD patients with co-morbidities remote monitoring of lung function by FOT and cardiac parameters did not change TTFH and EQ-5D. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01960907.

Bidragsytere

Paul P. Walker

  • Tilknyttet:
    Forfatter
    ved National Health Service
  • Tilknyttet:
    Forfatter
    ved University of Liverpool

Pasquale Pompilio

  • Tilknyttet:
    Forfatter
    ved Italia

Paolo Zanaboni

  • Tilknyttet:
    Forfatter
    ved Nasjonalt senter for e-helseforskning ved Universitetssykehuset Nord-Norge HF

Trine Strand Bergmo

  • Tilknyttet:
    Forfatter
    ved Nasjonalt senter for e-helseforskning ved Universitetssykehuset Nord-Norge HF

Kaiu Prikk

  • Tilknyttet:
    Forfatter
    ved Tallinna Tehnikaülikool
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