Cristin-resultat-ID: 1706696
Sist endret: 17. mars 2023, 11:44
NVI-rapporteringsår: 2019
Resultat
Vitenskapelig artikkel
2019

Using a period incidence survey to compare antibiotic use in children between a university hospital and a district hospital in a country with low antimicrobial resistance: a prospective observational study

Bidragsytere:
  • Christian Magnus Thaulow
  • Hege Salvesen Blix
  • Beate Horsberg Eriksen
  • Ingvild Ask
  • Tor Åge Myklebust og
  • Dag Berild

Tidsskrift

BMJ Open
ISSN 2044-6055
e-ISSN 2044-6055
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2019
Publisert online: 2019
Trykket: 2022
Volum: 9
Hefte: 5
Sider: 1 - 10
Artikkelnummer: e027836
Open Access

Importkilder

Scopus-ID: 2-s2.0-85066633780

Beskrivelse Beskrivelse

Tittel

Using a period incidence survey to compare antibiotic use in children between a university hospital and a district hospital in a country with low antimicrobial resistance: a prospective observational study

Sammendrag

Objectives To describe and compare antibiotic use in relation to indications, doses, adherence rate to guidelines and rates of broad-spectrum antibiotics (BSA) in two different paediatric departments with different academic cultures, and identify areas with room for improvement. Design Prospective observational survey of antibiotic use. Setting Paediatric departments in a university hospital (UH) and a district hospital (DH) in Norway, 2017. The registration period was 1 year at the DH and 4 months at the UH. Participants 201 children at the DH (mean age 3.8: SD 5.1) and 137 children at the UH (mean age 2.0: SD 5.9) were treated with systemic antibiotics by a paediatrician in the study period and included in the study. Outcome measures Main outcome variables were prescriptions of antibiotics, treatments with antibiotics, rates of BSA, median doses and adherence rate to national guidelines. Results In total, 744 prescriptions of antibiotics were given at the UH and 638 at the DH. Total adherence rate to guidelines was 75% at the UH and 69% at the DH (p=0.244). The rate of treatments involving BSA did not differ significantly between the hospitals (p=0.263). Use of BSA was related to treatment of central nervous system (CNS) infections, patients with underlying medical conditions or targeted microbiological treatment in 92% and 86% of the treatments, at the UH and DH, respectively (p=0.217). A larger proportion of the children at the DH were treated for respiratory tract infections (p

Bidragsytere

Christian Magnus Thaulow

  • Tilknyttet:
    Forfatter
    ved Klinikk for kvinner, barn og ungdom ved Helse Møre og Romsdal HF

Hege Salvesen Blix

  • Tilknyttet:
    Forfatter
    ved Avdeling for legemiddelstatistikk ved Folkehelseinstituttet
  • Tilknyttet:
    Forfatter
    ved Farmasøytisk institutt ved Universitetet i Oslo

Beate Horsberg Eriksen

  • Tilknyttet:
    Forfatter
    ved Klinikk for kvinner, barn og ungdom ved Helse Møre og Romsdal HF

Ingvild Ask

  • Tilknyttet:
    Forfatter
    ved Barnemedisinsk avdeling ved Oslo universitetssykehus HF

Tor Åge Myklebust

  • Tilknyttet:
    Forfatter
    ved Fagavdelinga ved Helse Møre og Romsdal HF
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