Cristin-resultat-ID: 1764879
Sist endret: 1. mars 2021, 14:34
NVI-rapporteringsår: 2019
Resultat
Vitenskapelig artikkel
2020

Pain Severity and Vitamin D Deficiency in IBD Patients

Bidragsytere:
  • Svein Oskar Frigstad
  • Marte Lie Høivik
  • Jørgen Jahnsen
  • Milada C Småstuen
  • Tore Grimstad
  • Ingrid Prytz Berset
  • mfl.

Tidsskrift

Nutrients
ISSN 2072-6643
e-ISSN 2072-6643
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2020
Publisert online: 2019
Trykket: 2020
Volum: 12
Hefte: 1
Sider: 1 - 12
Artikkelnummer: 26
Open Access

Importkilder

Scopus-ID: 2-s2.0-85077207239

Beskrivelse Beskrivelse

Tittel

Pain Severity and Vitamin D Deficiency in IBD Patients

Sammendrag

Background: Pain and vitamin D deficiency are common in inflammatory bowel disease (IBD). Disease activity, fatigue, frequent relapses, prior surgery and psychological factors all seem to influence the experience of pain in IBD. Vitamin D deficiency has been associated with muscle and skeletal pain. This study aimed to determine whether there is an association between vitamin D deficiency and severity of pain in patients with IBD, and to investigate the influence of other socio-demographic and psychological variables on the experience of pain. Methods: Patients with IBD were recruited from nine hospitals in Norway in a multicenter cross-sectional study. The Brief Pain Inventory (BPI) questionnaire was used to measure pain. Disease activity was assessed using clinical disease activity indices, C-reactive protein (CRP) and fecal calprotectin. Regression models were fitted to explore a possible association between 25-hydroxyvitamin D and pain severity. Results: Of 407 patients included in the analyses, 229 (56%) had Crohn's disease (CD) and 178 (44%) had ulcerative colitis (UC). Vitamin D deficiency was present in half (203/407) of patients. Presence of pain was reported by 76% (309/407). More severe pain was associated with female gender and increased disease activity scores, but not with increased CRP or fecal calprotectin. In CD, patients without prior intra-abdominal surgery reported more severe pain. In multivariate analyses, there was no association between 25-hydroxyvitamin D and pain severity. Conclusions: In this study, no significant association between pain severity and vitamin D deficiency was revealed in patients with IBD. Keywords: pain severity; patient reported outcomes; vitamin D deficiency.

Bidragsytere

Svein Oskar Frigstad

  • Tilknyttet:
    Forfatter
    ved Bærum sykehus ved Vestre Viken HF
  • Tilknyttet:
    Forfatter
    ved Gastromedisinsk avdeling ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Fag og utvikling ved Sykehuset Østfold HF
Aktiv cristin-person

Marte Lie Høivik

  • Tilknyttet:
    Forfatter
    ved Gastromedisinsk avdeling ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Gastromedisinsk avdeling ved Oslo universitetssykehus HF
Aktiv cristin-person

Jørgen Jahnsen

  • Tilknyttet:
    Forfatter
    ved Klinikk for indremedisin og lab fag ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Akershus universitetssykehus HF

Milada Cvancarova Småstuen

Bidragsyterens navn vises på dette resultatet som Milada C Småstuen
  • Tilknyttet:
    Forfatter
    ved Institutt for sykepleie og helsefremmende arbeid ved OsloMet - storbyuniversitetet
  • Tilknyttet:
    Forfatter
    ved Gastromedisinsk avdeling ved Oslo universitetssykehus HF

Tore Bjørn Grimstad

Bidragsyterens navn vises på dette resultatet som Tore Grimstad
  • Tilknyttet:
    Forfatter
    ved Helse Stavanger HF - Stavanger universitetssjukehus
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