Cristin-resultat-ID: 1791937
Sist endret: 10. februar 2020, 12:38
NVI-rapporteringsår: 2019
Resultat
Vitenskapelig artikkel
2019

Benefits of Hybrid Methods (PET/CT, PET MRI) in the Diagnosis of Abdominal Aortic Pathology

Bidragsytere:
  • Jiří Moláček
  • Jan Baxa
  • Václav Opatrný
  • Vladislav Třeška
  • Ivana Hollan og
  • Jiří Ferda

Tidsskrift

Rozhledy v Chirurgii
ISSN 0035-9351
e-ISSN 1805-4579
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2019
Trykket: 2019
Volum: 98
Hefte: 11
Sider: 450 - 456

Beskrivelse Beskrivelse

Tittel

Benefits of Hybrid Methods (PET/CT, PET MRI) in the Diagnosis of Abdominal Aortic Pathology

Tittel

Benefits of Hybrid Methods (PET/CT, PET MRI) in the Diagnosis of Abdominal Aortic Pathology

Sammendrag

Introduction: Ultrasound and CT angiography are common diagnostic methods of abdominal aortic pathologies. In the last decade, hybrid methods (PET/CT, PET/MRI) have become more common in this diagnostic algorithm. Originally they were indicated in malignancies or inflammatory processes. Currently, efforts are developed to visualize possible local inflammatory activity in the aortic wall and thus to assess a certain “disease activity” with the goal to anticipate further development of aortic pathology. The aim of our study was to analyze potential benefits of hybrid methods in predicting abdominal aortic pathology progression. Methods: In this prospective, open-label, observational study we examined 75 patients referred to PET/CT (N=61) or PET/MRI (N=14) due to any aortic pathology in 2015-2017. The patients included those with abdominal aortic aneurysm (AAA) (N=48; 64%), aortitis (N=5; 6.7%), aortic dissection (N=4; 5.3%), patients undergoing EVAR (N=6; 8%), patients with excessive atherosclerosis (N=7; 9.3%), patients with concomitant AAA and retroperitoneal fibrosis (N=4; 5.3%) and patient with an intramural hematoma (N=1; 1.3%). The minimum follow-up period was 6 months (0.5-2.5 years). Clinical symptoms, aortic diameter, growth rate and CRP levels were analyzed during the follow-up and correlation with PET/CT or PET/MRI findings was evaluated. Results: Increased metabolic activity in the aorta was found in 25 of the 75 examined patients (33.3%). Based on statistical analysis there were no associations between increased activity based on PET/CT or PET/MRI in the aortic wall and disease symptoms or progression. Conclusion: Our results provide no evidence that hybrid methods can predict further development of pathological findings in the abdominal aorta. PET/CT- or PET/MRI-based activity did not correlate with disease symptoms, AAA progression rate or dissection, either. Our results are also supported by some recent literature data. Keywords: Aorta; PET/CT; PET/MRI; aneurysm; dissection.

Bidragsytere

Jiri Molacek

Bidragsyterens navn vises på dette resultatet som Jiří Moláček
  • Tilknyttet:
    Forfatter
    ved Tsjekkia

J Baxa

Bidragsyterens navn vises på dette resultatet som Jan Baxa
  • Tilknyttet:
    Forfatter
    ved Tsjekkia

V Opatrny

Bidragsyterens navn vises på dette resultatet som Václav Opatrný
  • Tilknyttet:
    Forfatter
    ved Tsjekkia

Vladislav Treska

Bidragsyterens navn vises på dette resultatet som Vladislav Třeška
  • Tilknyttet:
    Forfatter
    ved Tsjekkia

Ivana Hollan

  • Tilknyttet:
    Forfatter
    ved Revmatismesykehuset AS
  • Tilknyttet:
    Forfatter
    ved Brigham and Women's Hospital
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