Cristin-resultat-ID: 1796024
Sist endret: 29. mars 2020, 19:31
NVI-rapporteringsår: 2019
Resultat
Vitenskapelig oversiktsartikkel/review
2019

Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries

Bidragsytere:
  • Ayesha Sania
  • Christopher R. Sudfeld
  • Goodarz Danaei
  • Günther Fink
  • Dana C. McCoy
  • Zhaozhong Zhu
  • mfl.

Tidsskrift

BMJ Open
ISSN 2044-6055
e-ISSN 2044-6055
NVI-nivå 1

Om resultatet

Vitenskapelig oversiktsartikkel/review
Publiseringsår: 2019
Volum: 9:e026449
Hefte: 10
Sider: 1 - 13
Artikkelnummer: e026449
Open Access

Importkilder

Scopus-ID: 2-s2.0-85072932180

Beskrivelse Beskrivelse

Tittel

Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries

Sammendrag

Objective To determine the magnitude of relationships of early life factors with child development in low/middle-income countries (LMICs). Design Meta-analyses of standardised mean differences (SMDs) estimated from published and unpublished data. Data sources We searched Medline, bibliographies of key articles and reviews, and grey literature to identify studies from LMICs that collected data on early life exposures and child development. The most recent search was done on 4 November 2014. We then invited the first authors of the publications and investigators of unpublished studies to participate in the study. Eligibility criteria for selecting studies Studies that assessed at least one domain of child development in at least 100 children under 7 years of age and collected at least one early life factor of interest were included in the study. Analyses Linear regression models were used to assess SMDs in child development by parental and child factors within each study. We then produced pooled estimates across studies using random effects meta-analyses. Results We retrieved data from 21 studies including 20 882 children across 13 LMICs, to assess the associations of exposure to 14 major risk factors with child development. Children of mothers with secondary schooling had 0.14 SD (95% CI 0.05 to 0.25) higher cognitive scores compared with children whose mothers had primary education. Preterm birth was associated with 0.14 SD (–0.24 to –0.05) and 0.23 SD (–0.42 to –0.03) reductions in cognitive and motor scores, respectively. Maternal short stature, anaemia in infancy and lack of access to clean water and sanitation had significant negative associations with cognitive and motor development with effects ranging from −0.18 to −0.10 SDs. Conclusions Differential parental, environmental and nutritional factors contribute to disparities in child development across LMICs. Targeting these factors from prepregnancy through childhood may improve health and development of children. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Bidragsytere

Ayesha Sania

  • Tilknyttet:
    Forfatter
    ved Columbia University in the City of New York

Christopher R. Sudfeld

  • Tilknyttet:
    Forfatter
    ved Harvard School of Public Health

Goodarz Danaei

  • Tilknyttet:
    Forfatter
    ved Harvard School of Public Health

Günther Fink

  • Tilknyttet:
    Forfatter
    ved Schweizerisches Tropen- und Public Health-Institut

Dana C. McCoy

  • Tilknyttet:
    Forfatter
    ved Harvard University
1 - 5 av 45 | Neste | Siste »