Cristin-resultat-ID: 1825816
Sist endret: 19. februar 2021, 16:37
NVI-rapporteringsår: 2020
Resultat
Vitenskapelig artikkel
2020

More severe radiographic osteoarthritis is associated with increased improvements in patients' health state following a total knee arthroplasty

Bidragsytere:
  • Yasser Rehman
  • Maren Falch Lindberg
  • Kristine Arnljot
  • Caryl Gay
  • Anners Lerdal og
  • Arild Aamodt

Tidsskrift

Journal of Arthroplasty
ISSN 0883-5403
e-ISSN 1532-8406
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2020
Volum: 35
Hefte: 11
Open Access

Importkilder

Scopus-ID: 2-s2.0-85092098354

Klassifisering

Vitenskapsdisipliner

Medisinske fag

Emneord

Ortopedi

HRCS

  • Helsekategori: 12 - Muskulatur og skjelett
    Aktivitet: 2 - Årsaksforhold

Beskrivelse Beskrivelse

Tittel

More severe radiographic osteoarthritis is associated with increased improvements in patients' health state following a total knee arthroplasty

Sammendrag

Background To assess whether preoperative radiological severity of osteoarthritis (OA) is related to the level of improvement in patients’ health state measured 1 year after total knee arthroplasty (TKA). Methods Radiographic severity of OA was graded using the Kellgren-Lawrence (KL) classification. Two independent observers were blinded to patients’ outcome scores. Health-related quality of life was measured using EQ-5D-3L preoperatively and at 12-month follow-up. The 5 dimensions of the EQ-5D were converted into a health state index score. The association between KL grade and improvement in health state score was analyzed using multiple linear regression. Results Among 156 consecutive patients (68% females, mean age 69 years) who underwent primary TKA, 3 knees (2%) were classified as KL grade 2, 115 as KL grade 3 (74%), and 38 as KL grade 4 (24%). Follow-up rate was 77%. There was substantial intra-rater and inter-rater agreement (Cohen’s kappa = 0.80 and 0.79). Most patients (64%) had clinically significant improvement in their health state score 1 year after TKA. However, after adjusting for relevant covariates, patients with severe OA (KL grade 4) were found to have significantly more improvement in their health state score than patients with mild or moderate OA (KL grade 2 or 3, respectively). Separate analysis of the 5 EQ-5D dimensions showed that the KL group differences were most evident in the “usual activities” and “pain/discomfort” dimensions. Conclusion Patients with severe OA have significantly more improvement in their usual activities and pain/discomfort 1 year after TKA than patients with less severe OA.

Bidragsytere

Aktiv cristin-person

Yasser Rehman

  • Tilknyttet:
    Forfatter
    ved Klinikk for Kirurgi ved Lovisenberg Diakonale Sykehus
  • Tilknyttet:
    Forfatter
    ved Institutt for helse og samfunn ved Universitetet i Oslo
Aktiv cristin-person

Maren Falch Lindberg

  • Tilknyttet:
    Forfatter
    ved Klinikk for Kirurgi ved Lovisenberg Diakonale Sykehus
  • Tilknyttet:
    Forfatter
    ved Avdeling for folkehelsevitenskap ved Universitetet i Oslo

Kristine Arnljot

  • Tilknyttet:
    Forfatter
    ved Klinikk for Kirurgi ved Lovisenberg Diakonale Sykehus

Caryl Gay

  • Tilknyttet:
    Forfatter
    ved Forskningsavdelingen ved Lovisenberg Diakonale Sykehus
  • Tilknyttet:
    Forfatter
    ved University of California, San Francisco
Aktiv cristin-person

Anners Lerdal

  • Tilknyttet:
    Forfatter
    ved Forskningsavdelingen ved Lovisenberg Diakonale Sykehus
  • Tilknyttet:
    Forfatter
    ved Tverrfaglig helsevitenskap ved Universitetet i Oslo
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