Cristin-resultat-ID: 1827965
Sist endret: 11. desember 2020, 11:23
NVI-rapporteringsår: 2020
Resultat
Vitenskapelig artikkel
2020

Validation of the German Classification of Diverticular Disease (VADIS)-a prospective bicentric observational study

Bidragsytere:
  • Johannes C Lauscher
  • Johan F. Lock
  • Katja Aschenbrenner
  • Rahel M Strobel
  • Marja Leonhardt
  • Andrea Stroux
  • mfl.

Tidsskrift

International Journal of Colorectal Disease
ISSN 0179-1958
e-ISSN 1432-1262
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2020
Publisert online: 2020
Sider: 1 - 13

Importkilder

Scopus-ID: 2-s2.0-85090131877

Beskrivelse Beskrivelse

Tittel

Validation of the German Classification of Diverticular Disease (VADIS)-a prospective bicentric observational study

Sammendrag

Purpose: The German Classification of Diverticular Disease was introduced a few years ago. The aim of this study was to determine whether Classification of Diverticular Disease enables an exact stratification of different types of diverticular disease in terms of course and treatment. Methods: This was a prospective, bicentric observational trial. Patients aged ≥ 18 years with diverticular disease were prospectively included. The primary endpoint was the rate of recurrence within 2 year follow-up. Secondary outcome measures were Gastrointestinal Quality of Life Index, Quality of life measured by SF-36, frequency of gastrointestinal complaints, and postoperative complications. Results: A total of 172 patients were included. After conservative management, 40% of patients required surgery for recurrence in type 1b vs. 80% in type 2a/b (p = 0.04). Sixty percent of patients with type 2a (micro-abscess) were in need of surgery for recurrence vs. 100% of patients with type 2b (macro-abscess) (p = 0.11). Patients with type 2a reached 123 ± 15 points in the Gastrointestinal Quality of Life Index compared with 111 ± 14 in type 2b (p = 0.05) and higher scores in the "Mental Component Summary" scale of SF-36 (52 ± 10 vs. 43 ± 13; p = 0.04). Patients with recurrent diverticulitis without complications (type 3b) had less often painful constipation (30% vs. 73%; p = 0.006) when they were operated compared with conservative treatment. Conclusion: Differentiation into type 2a and 2b based on abscess size seems reasonable as patients with type 2b required surgery while patients with type 2a may be treated conservatively. Sigmoid colectomy in patients with type 3b seems to have gastrointestinal complaints during long-term follow-up. Trial registration: https://www.drks.de ID: DRKS00005576. Keywords: Classification; Conservative treatment; Diverticular disease; Prospective trial; Quality of life; Recurrence; Surgical treatment.

Bidragsytere

Johannes C Lauscher

  • Tilknyttet:
    Forfatter
    ved Tyskland

Johan F. Lock

  • Tilknyttet:
    Forfatter
    ved Tyskland

Katja Aschenbrenner

  • Tilknyttet:
    Forfatter
    ved Tyskland

Rahel M Strobel

  • Tilknyttet:
    Forfatter
    ved Tyskland

Marja Leonhardt

  • Tilknyttet:
    Forfatter
    ved Avd for TSB ved Sykehuset Innlandet HF
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