Cristin-resultat-ID: 1905404
Sist endret: 20. april 2021, 19:53
Resultat
Poster
2019

Would you like some extra mercury with your fish? Applying a causal inference framework to study diet as a source of exposure to environmental contaminants in early life

Bidragsytere:
  • Eleni Zoumpoulia Papadopoulou
  • Line Småstuen Haug
  • Amrit Kaur Sakhi
  • Xavier Basagaña
  • Maribel Casas
  • Sílvia Fernández-Barrés
  • mfl.

Presentasjon

Navn på arrangementet: 31st annual conference of the International Society for Environmental Epidemiology
Sted: Utrecht
Dato fra: 25. august 2019
Dato til: 28. august 2019

Arrangør:

Arrangørnavn: International Society for Environmental Epidemiology

Om resultatet

Poster
Publiseringsår: 2019

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Tittel

Would you like some extra mercury with your fish? Applying a causal inference framework to study diet as a source of exposure to environmental contaminants in early life

Sammendrag

Background: Diet is a major exposure pathway to several toxic environmental contaminants. Fish and fruits are essential contributors of a healthy diet as well as an established source of pops, heavy metals and pesticide residues. Pregnant women and young children are especially vulnerable to exposures to environmental contaminants, while a balanced diet during these periods is critical for optimal nutritional status. Methods: In a study of 1,301 mother-child pairs from six European birth cohorts we assessed maternal fish and fruit consumption during pregnancy and child diet at 6-12 years, as well as concentrations of pcbs, pfass, as, hg and organophosphate pesticide (op) metabolites. We applied causal inference methods to examine the effect of fish and fruit recommended intakes on contaminant exposure. Results: We estimated that a population of pregnant women in which everyone was consuming up to 3 fish servings/week would have marginal geometric mean pfna, as and hg blood concentrations -0.17 μg/L (95%CI=-0.26,-0.07 μg/L), -2.08 μg/L (95%CI=-2.62,-1.54 μg/L) and -1.02 μg/L (95%CI=-1.39,-0.65 μg/L) lower than if exceeding the fish recommendations. Similarly, if the whole children population was consuming up to 2 fish servings/week they would have -0.03 μg/L and -0.46 μg/L lower pfunda and pfos blood levels and - 0.81 μg/l and -0.73 μg/L lower as and hg levels than if exceeding the recommendation. If the whole population of pregnant women were consuming at least two servings of fruits per day, it would result in 4.51 μg/g creatinine higher dmp levels, compared to less fruit. No significant increase of urinary op pesticide metabolites was found in children. Conclusion: Fish consumption is related to pfas, hg and as exposures, which could be effectively reduced by not exceeding the fish recommendations. Fruit consumption is a source of exposure to OP pesticides and adherence to the fruit recommendation could result in higher exposures.

Bidragsytere

Eleni Zoumpoulia Papadopoulou

  • Tilknyttet:
    Forfatter
    ved Smittevern ved Folkehelseinstituttet

Line Småstuen Haug

  • Tilknyttet:
    Forfatter
    ved Smittevern ved Folkehelseinstituttet

Amrit Kaur Sakhi

  • Tilknyttet:
    Forfatter
    ved Smittevern ved Folkehelseinstituttet

Xavier Basagaña

  • Tilknyttet:
    Forfatter

Maribel Casas

  • Tilknyttet:
    Forfatter
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