Cristin-resultat-ID: 1910170
Sist endret: 2. desember 2021, 18:00
NVI-rapporteringsår: 2021
Resultat
Vitenskapelig artikkel
2021

Mitigating Antibiotic Resistance Genes in Wastewater by Sequential Treatment with Novel Nanomaterials

Bidragsytere:
  • Lisa Paruch
  • Adam Paruch
  • Tanta-Verona Iordache
  • Andreea Gabriela Olaru og
  • Andrei Sarbu

Tidsskrift

Polymers
ISSN 2073-4360
e-ISSN 2073-4360
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2021
Publisert online: 2021
Volum: 13
Hefte: 10
Artikkelnummer: 1593
Open Access

Importkilder

Scopus-ID: 2-s2.0-85106660863

Beskrivelse Beskrivelse

Tittel

Mitigating Antibiotic Resistance Genes in Wastewater by Sequential Treatment with Novel Nanomaterials

Sammendrag

Wastewater (WW) has been widely recognized as the major sink of a variety of emerging pathogens (EPs), antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs), which may disseminate and impact wider environments. Improving and maximizing WW treatment efficiency to remove these microbial hazards is fundamentally imperative. Despite a variety of physical, biological and chemical treatment technologies, the efficiency of ARG removal is still far from satisfactory. Within our recently accomplished M-ERA.NET project, novel functionalized nanomaterials, i.e., molecularly imprinted polymer (MIP) films and quaternary ammonium salt (QAS) modified kaolin microparticles, were developed and demonstrated to have significant EP removal effectiveness on both Gram-positive bacteria (GPB) and Gram-negative bacteria (GNB) from WW. As a continuation of this project, we took the further step of exploring their ARG mitigation potential. Strikingly, by applying MIP and QAS functionalized kaolin microparticles in tandem, the ARGs prevalent in wastewater treatment plants (WWTPs), e.g., blaCTXM, ermB and qnrS, can be drastically reduced by 2.7, 3.9 and 4.9 log (copies/100 mL), respectively, whereas sul1, tetO and mecA can be eliminated below their detection limits. In terms of class I integron-integrase I (intI1), a mobile genetic element (MGE) for horizontal gene transfer (HGT), 4.3 log (copies/100 mL) reduction was achieved. Overall, the novel nanomaterials exhibit outstanding performance on attenuating ARGs in WW, being superior to their control references. This finding provides additional merit to the application of developed nanomaterials for WW purification towards ARG elimination, in addition to the proven bactericidal effect.

Bidragsytere

Lisa Paruch

Bidragsyterens navn vises på dette resultatet som Lisa Paruch
  • Tilknyttet:
    Forfatter
    ved Divisjon for miljø og naturressurser ved Norsk institutt for bioøkonomi
Aktiv cristin-person

Adam Paruch

  • Tilknyttet:
    Forfatter
    ved Divisjon for miljø og naturressurser ved Norsk institutt for bioøkonomi

Tanta-Verona Iordache

  • Tilknyttet:
    Forfatter
    ved Romania

Andreea Gabriela Olaru

  • Tilknyttet:
    Forfatter
    ved Romania

Andrei Sarbu

  • Tilknyttet:
    Forfatter
    ved Romania
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