Cristin-resultat-ID: 1919439
Sist endret: 10. januar 2022, 14:16
NVI-rapporteringsår: 2021
Resultat
Vitenskapelig artikkel
2021

The course of depressive symptoms and mortality in older patients with cancer

Bidragsytere:
  • Tom Borza
  • Magnus Harneshaug
  • Lene Kirkhus
  • Jūratė Šaltytė Benth
  • Geir Selbæk
  • Sverre Bergh
  • mfl.

Tidsskrift

Aging & Mental Health
ISSN 1360-7863
e-ISSN 1364-6915
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2021
Publisert online: 2021
Sider: 1 - 8
Open Access

Importkilder

Scopus-ID: 2-s2.0-85108369667

Beskrivelse Beskrivelse

Tittel

The course of depressive symptoms and mortality in older patients with cancer

Sammendrag

Objective: The Geriatric Depression Scale (GDS-15), a self-report questionnaire, emphasizes the psychological dimension of depression. We aimed to investigate whether GDS-15 scores were associated with mortality in older patients with cancer and describe the course of individual symptoms on the GDS-15. Methods: An observational, multicenter, prospective study of 288 patients 70 years or older with cancer followed over 24 months. The patients were assessed with the GDS-15 at inclusion, and after four and 12 months. An extended Cox regression model assessed the association between time-dependent GDS-15 scores and mortality. Results: After adjusting for cancer-related prognostic factors, a one-point increase in GDS-15 sum score increased risk of death by 12%. GDS-15 mean score increased during the first four months of the study, as did odds for the presence of the GDS-15 symptoms 'feel you have more problems with memory than most', 'not feel full of energy', and 'think that most people are better off than you'. The most prevalent and persistent GDS-15 symptom was 'prefer to stay at home, rather than going out and doing new things', and 'not to be in good spirits most of the time' was the least prevalent. Conclusions: More severe depressive symptoms, as measured by the GDS-15, were associated with higher mortality in older patients with cancer. The importance of emotional distress and how to alleviate it should be investigated further in these patients. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

Bidragsytere

Tom Borza

  • Tilknyttet:
    Forfatter
    ved Avd Alderspsykiatri ved Sykehuset Innlandet HF

Magnus Harneshaug

  • Tilknyttet:
    Forfatter
    ved Avd Alderspsykiatri ved Sykehuset Innlandet HF
  • Tilknyttet:
    Forfatter
    ved Avdeling for kreftbehandling ved Universitetet i Oslo

Lene Kirkhus

  • Tilknyttet:
    Forfatter
    ved Kreftklinikken ved Oslo universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Avd Alderspsykiatri ved Sykehuset Innlandet HF
Aktiv cristin-person

Jurate Saltyte Benth

Bidragsyterens navn vises på dette resultatet som Jūratė Šaltytė Benth
  • Tilknyttet:
    Forfatter
    ved Helsetjenesteforskning (HØKH) ved Akershus universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Klinikk for helsetjenesteforskning og psykiatri ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Avd Alderspsykiatri ved Sykehuset Innlandet HF
Aktiv cristin-person

Geir Selbæk

  • Tilknyttet:
    Forfatter
    ved Geriatrisk avdeling ved Oslo universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Geriatrisk avdeling ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Nasjonalt senter for aldring og helse ved Sykehuset i Vestfold HF
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