Cristin-resultat-ID: 1944982
Sist endret: 22. februar 2022, 15:29
NVI-rapporteringsår: 2021
Resultat
Vitenskapelig artikkel
2021

Factors associated with the level of prolactin in patients under remission from Alcohol Use Disorder: A gender perspective

Bidragsytere:
  • Susmita Pandey
  • Ingeborg Bolstad
  • Lars Lien og
  • Jørgen Gustav Bramness

Tidsskrift

Neuropsychopharmacology Reports
ISSN 2574-173X
e-ISSN 2574-173X
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2021
Publisert online: 2021
Volum: 41
Hefte: 3
Sider: 352 - 361
Open Access

Importkilder

Scopus-ID: 2-s2.0-85105148974

Beskrivelse Beskrivelse

Tittel

Factors associated with the level of prolactin in patients under remission from Alcohol Use Disorder: A gender perspective

Sammendrag

Background: Prolactin mirrors the dopaminergic activity in the brain which is key to understanding alcohol use disorders (AUD). Still, patients with AUD are a heterogenous group and there seem to be gender differences in the relationship between alcohol use and the level of prolactin. In this study, we examined gender-wise relationship of alcohol use trait- and state-related factors with the level of prolactin among AUD inpatients in remission. Methods: This cross-sectional study examined the level of prolactin along with general patient characteristics and alcohol use trait- and state-related factors that could influence the level of prolactin in 112 AUD inpatients at three rehabilitation clinics in Norway. Logistic regression was performed to identify the gender-specific predictors of level of prolactin. Results: Male and female AUD patients had similar level of prolactin. Among females, younger age, early alcohol debut, and absence of parental drinking problem predicted higher level of prolactin. In males, presence of other substance dependence predicted a lower level of prolactin. Conclusions: There were gender differences in the factors associated with the level of prolactin among the AUD patients. Especially in the female AUD patients under remission, alcohol use trait-related factors were better predictors of the level of prolactin than the alcohol use state-related factors, indicating that individuals might characteristically have varying degree of dopamine reactivity. Keywords: alcohol use disorder; gender; prolactin; state factors; trait factors. © 2021 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of Neuropsychopharmacology.

Bidragsytere

Susmita Pandey

  • Tilknyttet:
    Forfatter
    ved Klinikk psykisk helse og avhengighet ved Universitetet i Oslo
  • Tilknyttet:
    Forfatter
    ved Avd for TSB ved Sykehuset Innlandet HF

Ingeborg Bolstad

  • Tilknyttet:
    Forfatter
    ved Avd for TSB ved Sykehuset Innlandet HF
Aktiv cristin-person

Lars Lien

  • Tilknyttet:
    Forfatter
    ved Institutt for helse- og sykepleievitenskap ved Høgskolen i Innlandet
  • Tilknyttet:
    Forfatter
    ved Avd for TSB ved Sykehuset Innlandet HF

Jørgen Gustav Bramness

  • Tilknyttet:
    Forfatter
    ved Psykiatri ved UiT Norges arktiske universitet
  • Tilknyttet:
    Forfatter
    ved Avd for TSB ved Sykehuset Innlandet HF
  • Tilknyttet:
    Forfatter
    ved Avdeling for rusmidler og tobakk ved Folkehelseinstituttet
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