Cristin-resultat-ID: 1954465
Sist endret: 15. november 2021, 09:25
Resultat
Poster
2021

Task-dependent EEG changes in adult ADHD

Bidragsytere:
  • Andras Puszta
  • Rene Jürgen Huster
  • Anne-Kristin Solbakk
  • Ingrid Funderud
  • Tor Endestad og
  • Venke Arntsberg Grane

Presentasjon

Navn på arrangementet: 8th World congress on ADHD
Dato fra: 6. mai 2021
Dato til: 9. mai 2021

Om resultatet

Poster
Publiseringsår: 2021

Beskrivelse Beskrivelse

Tittel

Task-dependent EEG changes in adult ADHD

Sammendrag

Objectives Our aim for the current study was twofold: First, delineate how brain connectivity differs between the on-task state during a Go-NoGo task and resting state, and whether these differences are affected by ADHD. Second, we investigated how ADHD impacts event-related potentials and brain oscillations during response inhibition. While the former aim was investigated in an exploratory manner, for the second aim our hypothesis was that P300 amplitude and theta power are decreased in ADHD. Methods We analysed EEG-datasets of 35 adult ADHD patients and a matched healthy control group. EEG was recorded while participants performed a Go-NoGo task and during resting-state. We investigated gamma phase connectivity in the task- and resting state across groups. For the Go-NoGo task, we analysed P300 peak amplitude and latency as well as theta power across conditions and groups. Furthermore, we compared behavioral performance between groups, and evaluated within-group correlations of behavior and EEG parameters. Results We observed a significant main effect of Group for gamma phase connectivity, reflecting increased connectivity in the ADHD- compared to control-group during the task state . We also observed more commission errors in the ADHD-group. NoGo-P300 amplitudes were attenuated and peaked earlier (only over frontal leads) in ADHD patients. Moreover, there was a significant negative correlation between reaction time and both frontal theta power and Go- P300 amplitude in the healthy control but not the ADHD-group. Conclusions Overall, we replicated the ERP-changes reported in earlier studies and behavioral signs of increased impulsivity. The results indicate that ADHD impacts neural indices of response inhibition, but (at least in the ADHD cohort) the neural indices did not not correlate with performance. Furthermore, our results suggest that frontal gamma-band phase connectivity during task state could be a possible neural marker of ADHD.

Bidragsytere

Andras Puszta

  • Tilknyttet:
    Forfatter
    ved Helgelandssykehuset HF

Rene Jürgen Huster

  • Tilknyttet:
    Forfatter
    ved Kognitiv- og nevropsykologi ved Universitetet i Oslo

Anne-Kristin Solbakk

  • Tilknyttet:
    Forfatter
    ved Kognitiv- og nevropsykologi ved Universitetet i Oslo

Ingrid Funderud

  • Tilknyttet:
    Forfatter
    ved Helgelandssykehuset HF

Tor Endestad

  • Tilknyttet:
    Forfatter
    ved Kognitiv- og nevropsykologi ved Universitetet i Oslo
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