Cristin-resultat-ID: 2028737
Sist endret: 1. juni 2022, 13:24
Resultat
Vitenskapelig foredrag
2022

Spasticity treatments and orthopedic surgeries in lower extremities in children with cerebral palsy – a longitudinal population based study

Bidragsytere:
  • Anne Elisabeth Ross Raftemo
  • Reidun Birgitta Jahnsen
  • Siri Brandvik
  • Sandra Julsen Hollung
  • Manuela Zucknick og
  • Guro Lillemoen Andersen

Presentasjon

Navn på arrangementet: Combined 11th Australasian Academy of Cerebral Palsy and Developmental Medicine and the 3rd International Alliance of Academies of Childhood Disability 'Better Together' Conference 2022
Sted: Melbourne, Australia
Dato fra: 1. mars 2022
Dato til: 5. mars 2022

Arrangør:

Arrangørnavn: AusACPDM

Om resultatet

Vitenskapelig foredrag
Publiseringsår: 2022

Beskrivelse Beskrivelse

Tittel

Spasticity treatments and orthopedic surgeries in lower extremities in children with cerebral palsy – a longitudinal population based study

Sammendrag

Background/objectives: Intramuscular injections of Botulinum toxin A (BoNT-A) have been used to reduce spasticity in children with cerebral palsy (CP) for several decades. Despite extensive use, there is a lack of evidence-based treatment guidelines, and the optimal use of BoNT-A injections and other treatments to reduce tone and prevent contractures in children with CP is a matter of discussion. The aim of this study is to describe the use of BoNT-A treatments, Intrathecal baclofen and orthopedic surgery over a 20-year period in children with CP in Norway. Study design: National register-based longitudinal study Study participants & setting: Children with spastic, dyskinetic or unclassified CP born 2002 to 2010 with information on gross motor function recorded from 2002 to 2019 in the Norwegian Quality and Surveillance Registry for Cerebral Palsy (NorCP) were included. Materials/methods: We present a descriptive analysis of the distributions (N, %) of BoNT-A treatment, Intrathecal baclofen and orthopedic surgery by age, the Gross Motor Function Classification System (GMFCS) level, CP diagnosis, by muscle (BoNT-A) and type of surgery. Lexis diagrams describe the change in distributions of BoNT-A treatment, Intrathecal baclofen and orthopedic surgery for age cohorts over time. Results: Among 1010 eligible children 567 (56%) received BoNT-A in the lower extremities at least once. Among these 447 (88%) received the first treatment before the age of eight years. BoNT-A treatment was most often given to children on GMFCS level III (44, 77%). Most children received BoNT-A injections in the gastrocnemius muscle (387, 71%), the soleus muscle (251, 46%) and the hamstrings muscles (198, 37%). Among the eligible children 61 (6%) were treated with Intrathecal baclofen, and 58 (95%) of these were classified on GMFCS level IV and V. Of the 345 children (35%) who received orthopedic surgery, the highest proportion had spastic quadriplegia (93, 66%) and GMFCS level IV (53, 63%). Conclusions/significance: A high proportion of children with CP in Norway received BoNT-A, most often in the gastrocnemius muscle. Lexis diagrams will describe the changes in distributions of the treatments for age cohorts over time. This information will be used to support healthcare planning for children with CP in Norway.

Bidragsytere

Anne Elisabeth Ross Raftemo

  • Tilknyttet:
    Forfatter
    ved Institutt for klinisk og molekylær medisin ved Norges teknisk-naturvitenskapelige universitet
  • Tilknyttet:
    Forfatter
    ved Medisinsk klinikk ved Sykehuset i Vestfold HF

Reidun Birgitta Jahnsen

  • Tilknyttet:
    Forfatter
    ved Sunnaas sykehus HF
  • Tilknyttet:
    Forfatter
    ved Barneavdeling for nevrofag ved Oslo universitetssykehus HF

Siri Brandvik

  • Tilknyttet:
    Forfatter
    ved Norges teknisk-naturvitenskapelige universitet

Sandra Julsen Hollung

  • Tilknyttet:
    Forfatter
    ved Medisinsk klinikk ved Sykehuset i Vestfold HF

Manuela Zucknick

  • Tilknyttet:
    Forfatter
    ved Statistisk læring i molekylærmedisin ved Universitetet i Oslo
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