Cristin-resultat-ID: 523730
Sist endret: 13. januar 2011 16:17
Resultat
Vitenskapelig foredrag
2010

Cochrane review update 2010: Sustained-release naltrexone for opioid dependence

Bidragsytere:
  • Philipp Paul Lobmaier
  • Nikolaj Kunøe og
  • Hege Kornør

Presentasjon

Navn på arrangementet: ISAM 2010
Sted: Milan
Dato fra: 3. oktober 2010
Dato til: 7. oktober 2010

Arrangør:

Arrangørnavn: Interantional Society of Addiction Medicine

Om resultatet

Vitenskapelig foredrag
Publiseringsår: 2010

Beskrivelse Beskrivelse

Tittel

Cochrane review update 2010: Sustained-release naltrexone for opioid dependence

Sammendrag

Naltrexone is an opioid receptor antagonist that blocks the effects of opioids such as heroin and morphine. Naltrexone has no abuse potential, mild and transient side effects and thus appears an ideal pharmacotherapy for opioid dependence. Limited compliance with oral naltrexone treatment is a known drawback. Several naltrexone implant and injectable depot formulations are being investigated and provide naltrexone release for at least one month. During the last couple of years several reports on new formulations have been published. This presentation gives an update on the systematic Cochrane review first published in 2008 on naltrexone injectables and implants for opioid dependence. The new systematic search was conducted in August 2010. To evaluate effectiveness only randomised-controlled trials (RCTs) were included. Reviewers independently evaluated the reports, rated methodological quality and extracted data. When appropriate, meta-analyses were performed for pre-specified outcome measures. The systematic search identified 685 reports as possibly relevant. The findings from the RCTs that were included will be presented at the meeting.

Bidragsytere

Aktiv cristin-person

Philipp Paul Lobmaier

  • Tilknyttet:
    Forfatter
    ved Senter for rus- og avhengighetsforskning ved Universitetet i Oslo
Aktiv cristin-person

Nikolaj Kunøe

  • Tilknyttet:
    Forfatter
    ved Institutt for psykiatri ved Universitetet i Oslo
Aktiv cristin-person

Hege Kornør

  • Tilknyttet:
    Forfatter
    ved Folkehelseinstituttet
1 - 3 av 3