Cristin-resultat-ID: 527620
Sist endret: 4. juli 2011 13:26
NVI-rapporteringsår: 2010
Resultat
Vitenskapelig artikkel
2010

How the brain integrates costs and benefits during decision making

Bidragsytere:
  • Ulrike Basten
  • Guido Biele
  • Hauke R. Heekeren og
  • Christian J. Fiebach

Tidsskrift

Proceedings of the National Academy of Sciences of the United States of America
ISSN 0027-8424
e-ISSN 1091-6490
NVI-nivå 2

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2010
Volum: 107
Hefte: 50
Sider: 21767 - 21772

Importkilder

Isi-ID: 000285521500097

Beskrivelse Beskrivelse

Tittel

How the brain integrates costs and benefits during decision making

Sammendrag

When we make decisions, the benefits of an option often need to be weighed against accompanying costs. Little is known, however, about the neural systems underlying such cost-benefit computations. Using functional magnetic resonance imaging and choice modeling, we show that decision making based on cost-benefit comparison can be explained as a stochastic accumulation of cost-benefit difference. Model-driven functional MRI shows that ventromedial and left dorsolateral prefrontal cortex compare costs and benefits by computing the difference between neural signatures of anticipated benefits and costs from the ventral striatum and amygdala, respectively. Moreover, changes in blood oxygen level dependent (BOLD) signal in the bilateral middle intraparietal sulcus reflect the accumulation of the difference signal from ventromedial prefrontal cortex. In sum, we show that a neurophysiological mechanism previously established for perceptual decision making, that is, the difference-based accumulation of evidence, is fundamental also in value-based decisions. The brain, thus, weighs costs against benefits by combining neural benefit and cost signals into a single, difference-based neural representation of net value, which is accumulated over time until the individual decides to accept or reject an option.

Bidragsytere

Ulrike Basten

  • Tilknyttet:
    Forfatter
    ved Johann Wolfgang Goethe-Universität Frankfurt am Main
Aktiv cristin-person

Guido Philipp Emmanuel Biele

Bidragsyterens navn vises på dette resultatet som Guido Biele
  • Tilknyttet:
    Forfatter
    ved Freie Universität Berlin
  • Tilknyttet:
    Forfatter
    ved Max-Planck-Institut für Bildungsforschung
  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo

Hauke R. Heekeren

  • Tilknyttet:
    Forfatter
    ved Freie Universität Berlin
  • Tilknyttet:
    Forfatter
    ved Max-Planck-Gesellschaft

Christian J. Fiebach

  • Tilknyttet:
    Forfatter
    ved Bernstein Center for Computational Neuroscience
  • Tilknyttet:
    Forfatter
    ved Johann Wolfgang Goethe-Universität Frankfurt am Main
  • Tilknyttet:
    Forfatter
    ved Radboud Universiteit
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