Cristin-resultat-ID: 932263
Sist endret: 25. oktober 2016 14:33
NVI-rapporteringsår: 2013
Resultat
Vitenskapelig artikkel
2013

The association between prescribed opioid use for mothers and children: a record-linkage study

Bidragsytere:
  • Tomas Log
  • Svetlana Skurtveit
  • Randi Marie Selmer
  • Aage Tverdal
  • Kari Furu og
  • Ingeborg Hartz

Tidsskrift

European Journal of Clinical Pharmacology
ISSN 0031-6970
e-ISSN 1432-1041
NVI-nivå 2

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2013
Publisert online: 2012
Trykket: 2013
Volum: 69
Hefte: 1
Sider: 111 - 118

Importkilder

Isi-ID: 000313072600011

Klassifisering

Vitenskapsdisipliner

Farmakologi

Emneord

Opioider • Mor-barn helse • Medisinering • Avhengighet

Beskrivelse Beskrivelse

Tittel

The association between prescribed opioid use for mothers and children: a record-linkage study

Sammendrag

Abstract Purpose The repeated use of prescription opioids may lead to serious side effects. It is therefore important to examine factors associated with such repeated use. The aim of this study was to investigate the association between the maternal use of prescription opioids and their use by offspring of these mothers. Methods Data were extracted from two nationwide registers linked by unique personal identity numbers: the 2001 Norwegian Population and Housing Census and the Norwegian Prescription Database 2004–2009. The study population consisted of 97,574 adolescents aged 15–16 years in 2001 and their mothers. The repeated use of opioids was defined as the issuing of >4 and >15 prescriptions to an adolescent and his/her mother, respectively, during the period 2004–2009. Non-steroidal anti-inflammatory drugs (NSAIDs) are not potentially addictive, and individuals issued prescriptions for NSAIDs were used as the reference analgesic drug group. Results The proportion of repeated prescription opioid users was higher among adolescents whose mother was registered as a repeated user of prescription opioids (8.4 %) than among those whose mother did not repeatedly use prescription opioids (2.4 %). The odds ratio (OR) was 3.1 [95 % confidence interval (CI) 2.7–3.6] when adjusted for the mother’s socioeconomic characteristics and the gender of the offspring. A lower socioeconomic position of the mother increased the risk of repeated opioid use by her offspring. Maternal repeated use of NSAIDs was associated with repeated use of NSAIDs among offspring (OR 1.8, 95 % CI 1.7–2.0). Conclusions Among our study population, the maternal use of opioids was associated with the repeated use of prescription opioids among the respective offspring. The same association was seen with NSAIDs, but to a lesser extent.

Bidragsytere

Tomas Log

  • Tilknyttet:
    Forfatter
    ved Forskningsgruppe i mikrobiologi ved UiT Norges arktiske universitet

Svetlana Skurtveit

  • Tilknyttet:
    Forfatter
    ved Avdeling for psykiske lidelser ved Folkehelseinstituttet
  • Tilknyttet:
    Forfatter
    ved Senter for rus- og avhengighetsforskning ved Universitetet i Oslo

Randi Marie Selmer

  • Tilknyttet:
    Forfatter
    ved Avdeling for kroniske sykdommer og aldring ved Folkehelseinstituttet

Aage Tverdal

  • Tilknyttet:
    Forfatter
    ved Folkehelseinstituttet

Kari Furu

  • Tilknyttet:
    Forfatter
    ved Forskningsgruppe i mikrobiologi ved UiT Norges arktiske universitet
  • Tilknyttet:
    Forfatter
    ved Avdeling for kroniske sykdommer og aldring ved Folkehelseinstituttet
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