Studie for å undersøke effekten av smertelindring ved perifer kryoneurolyse sammenlignet med kontrollbehandling hos voksne med trigeminusnevralgi.

The CryoGem Trial is a research study that tests a freezing technique of nerves to see if it helps relieve pain in adults with trigeminal neuralgia, a condition that causes severe facial pain. In this study, we want to find out if the freezing technique is effective and safe. We will do this by comparing two groups of adults with trigeminal neuralgia. We will recruit up to 24 adults with trigeminal neuralgia to take part in this study. All participants will keep a daily diary for two weeks to track their headaches before being randomised to treatment or sham therapy. For the next four weeks, participants in both groups will continue recording their headaches without knowing which treatment they are receiving. After this initial period, there will be an extension period where all participants can receive treatment as needed for up to two years. If the study is positive we will know that the therapy has a potential that warrants a bigger pivotal study.