Aziridines from L-Aspartic Acid

Chiral aziridines from natural L-aspartic acid have been synthesized. One form of the aziridines is O-protected as a tert-butyl ester, while the other as a tosylate. Both forms have either BOC or tosylate as N-protecting group. These chiral compounds are intermediates in the development of a cost-effective totalsynthesis of substituted (S)-2-aminotetralins. The poster will present results in the synthesis of the different aziridines.