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Cristin-resultat-ID:
1383245
Sist endret:
16. februar 2017, 21:34
NVI-rapporteringsår:
2016
Resultat
Vitenskapelig artikkel
2016
Exposure of first-feeding cod larvae to dispersed crude oil results in similar transcriptional and metabolic responses as food deprivation
Bjørn Henrik Hansen
Kai Kristoffer Lie
Trond Røvik Størseth
Trond Nordtug
Dag Altin
og
Pål Asgeir Olsvik
Tidsskrift
Tidsskrift
Journal of Toxicology and Environmental Health, Part A
ISSN 1528-7394
e-ISSN 1087-2620
NVI-nivå 1
Finn i kanalregisteret
Om resultatet
Om resultatet
Vitenskapelig artikkel
Publiseringsår: 2016
Volum: 79
Hefte: 13-15
Sider: 558 - 571
Lenker
Lenker
original online (doi)
https://doi.org/10.1080/07317131.2016.1171985
Importkilder
Importkilder
Scopus-ID: 2-s2.0-84980607900
Scopus-ID: 2-s2.0-84982908345
Beskrivelse
Beskrivelse
Engelsk
Tittel
Exposure of first-feeding cod larvae to dispersed crude oil results in similar transcriptional and metabolic responses as food deprivation
Sammendrag
Exposure of first-feeding cod larvae (Gadus morhua) to dispersed oil results in reduced feeding during an important transition period. First-feeding cod larvae were subjected to a 4-d treatment of food deprivation and sampled for microarray analyses. These microarray data were combined with data from cod larvae treated with mechanically and chemically dispersed oil in an attempt to understand to what extent starvation might explain some of the effects observed in first-feeding cod larvae during oil exposure. Transcriptional profiling of cod larvae suggested that the influence of oil exposure was almost as dramatic as being completely deprived of food. Protein and cellular degradation and loss of amino acids and glucose appear to be concomitant responses to both oil exposure and starvation. Fluorescence imaging of gut content indicated low uptake of food, and reduced growth (decrease in dry weight and in carbon and nitrogen content) was also noted in oil-exposed larvae, providing phenotypic anchoring of microarray data. The study displays the importance in combining use of high-throughput molecular tools with assessment of fitness-related endpoints in order to provide a greater understanding of toxicant-induced responses. This combined-approach investigation suggests that reduction of food uptake is an important process to be included when predicting effects of accidental oil spills. Finally, when comparing data from two oil treatments, exposure to chemically dispersed oil did not appear to result in greater toxicity than exposure to mechanically dispersed oil.
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Bidragsytere
Bjørn Henrik Hansen
Forfatter
ved Klima og miljø ved SINTEF Ocean
Kai Kristoffer Lie
Forfatter
ved Marin toksikologi ved Havforskningsinstituttet
Trond Røvik Størseth
Forfatter
ved Klima og miljø ved SINTEF Ocean
Trond Nordtug
Forfatter
ved Klima og miljø ved SINTEF Ocean
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ved Diverse norske bedrifter og organisasjoner
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