Cristin-resultat-ID: 1402980
Sist endret: 11. mai 2017, 10:10
NVI-rapporteringsår: 2016
Resultat
Vitenskapelig artikkel
2017

Emotional conflict processing in adolescent chronic fatigue syndrome: A pilot study using functional magnetic resonance imaging

Bidragsytere:
  • Laura A Wortinger Bakke
  • Tor Endestad
  • Annika Maria D Melinder
  • Merete Glenne Øie
  • Dag Sulheim
  • Frode Even Fagermoen
  • mfl.

Tidsskrift

Journal of Clinical and Experimental Neuropsychology
ISSN 1380-3395
e-ISSN 1744-411X
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2017
Publisert online: 2016
Volum: 39
Hefte: 4
Sider: 355 - 368
Open Access

Importkilder

Scopus-ID: 2-s2.0-84988446648

Beskrivelse Beskrivelse

Tittel

Emotional conflict processing in adolescent chronic fatigue syndrome: A pilot study using functional magnetic resonance imaging

Sammendrag

Introduction: Studies of neurocognition suggest that abnormalities in cognitive control contribute to the pathophysiology of chronic fatigue syndrome (CFS) in adolescents, yet these abnormalities remain poorly understood at the neurobiological level. Reports indicate that adolescents with CFS are significantly impaired in conflict processing, a primary element of cognitive control. Method: In this study, we examine whether emotional conflict processing is altered on behavioral and neural levels in adolescents with CFS and a healthy comparison group. Fifteen adolescent patients with CFS and 24 healthy adolescent participants underwent functional magnetic resonance imaging (fMRI) while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect labeled words. Results: Adolescent CFS patients were less able to engage the left amygdala and left midposterior insula (mpINS) in response to conflict than the healthy comparison group. An association between accuracy interference and conflict-related reactivity in the amygdala was observed in CFS patients. A relationship between response time interference and conflict-related reactivity in the mpINS was also reported. Neural responses in the amygdala and mpINS were specific to fatigue severity. Conclusions: These data demonstrate that adolescent CFS patients displayed deficits in emotional conflict processing. Our results suggest abnormalities in affective and cognitive functioning of the salience network, which might underlie the pathophysiology of adolescent CFS.

Bidragsytere

Laura Anne Wortinger Bakke

Bidragsyterens navn vises på dette resultatet som Laura A Wortinger Bakke
  • Tilknyttet:
    Forfatter
    ved Barne- og ungdomsklinikken ved Akershus universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo

Tor Endestad

  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo
Aktiv cristin-person

Annika Maria Désirée Melinder

Bidragsyterens navn vises på dette resultatet som Annika Maria D Melinder
  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo
Aktiv cristin-person

Merete Glenne Øie

  • Tilknyttet:
    Forfatter
    ved Div Gjøvik/Lillehammer ved Sykehuset Innlandet HF
  • Tilknyttet:
    Forfatter
    ved Psykologisk institutt ved Universitetet i Oslo

Dag Sulheim

  • Tilknyttet:
    Forfatter
    ved Barnemedisinsk avdeling ved Oslo universitetssykehus HF
  • Tilknyttet:
    Forfatter
    ved Avd Barn Lillehammer ved Sykehuset Innlandet HF
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