Cristin-resultat-ID: 1678064
Sist endret: 19. februar 2019, 11:01
NVI-rapporteringsår: 2018
Resultat
Vitenskapelig artikkel
2018

In-field and out-of-file application in 12C ion therapy using fully 3D silicon microdosimeters

Bidragsytere:
  • Linh T. Tran
  • Lachlan Chartier
  • David Bolst
  • Jeremy Davis
  • Dale A. Prokopovich
  • Alex Pogossov
  • mfl.

Tidsskrift

Radiation Measurements
ISSN 1350-4487
e-ISSN 1879-0925
NVI-nivå 1

Om resultatet

Vitenskapelig artikkel
Publiseringsår: 2018
Volum: 115
Sider: 55 - 59
Open Access

Importkilder

Scopus-ID: 2-s2.0-85048802698

Beskrivelse Beskrivelse

Tittel

In-field and out-of-file application in 12C ion therapy using fully 3D silicon microdosimeters

Sammendrag

This paper presents recent development of Silicon on Insulator (SOI) detectors for microdosimetry at the Centre for Medical Radiation Physics (CMRP) at the University of Wollongong. A new CMRP SOI microdosimeter design, the 3D mushroom microdosimeter is presented. Modification of SOI design and changes to the fabrication processes have led to improved definition of the microscopic sensitive volumes (SV), and thus to better modelling of the deposition of ionizing energy in a biological cell. The electrical and charge collection properties of the devices have been presented in previous works. In this study, the response of the microdosimeters in monoenergetic and spread out Bragg peak therapeutic 12C ion beam at Heavy Ion Medical Accelerator in Chiba (HIMAC, Japan) are presented. Derived relative biological effectiveness (RBE) in 12C ion radiation therapy matches the tissue equivalent proportional counter (TEPC) well, along with outstanding spatial resolution. The use of SOI technology in experimental microdosimetry offers simplicity (no gas system or HV supply), high spatial resolution, low cost, high count rates capabilities for beam characterisation and quality assurance (QA) in charged particle therapy.

Bidragsytere

Linh T. Tran

  • Tilknyttet:
    Forfatter
    ved University of Wollongong

Lachlan Chartier

  • Tilknyttet:
    Forfatter
    ved University of Wollongong

David Bolst

  • Tilknyttet:
    Forfatter
    ved University of Wollongong

Jeremy Davis

  • Tilknyttet:
    Forfatter
    ved University of Wollongong

Dale A. Prokopovich

  • Tilknyttet:
    Forfatter
    ved University of Wollongong
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