Cristin-resultat-ID: 2049242
Sist endret: 13. november 2023, 12:41
NVI-rapporteringsår: 2022
Resultat
Vitenskapelig oversiktsartikkel/review
2023

Applying genetic technologies to combat infectious diseases in aquaculture

Bidragsytere:
  • Nicholas Andrew Robinson
  • Diego Robledo
  • Lene Sveen
  • Rose Ruiz Daniels
  • Aleksei Krasnov
  • Andrew Coates
  • mfl.

Tidsskrift

Reviews in Aquaculture
ISSN 1753-5123
e-ISSN 1753-5131
NVI-nivå 1

Om resultatet

Vitenskapelig oversiktsartikkel/review
Publiseringsår: 2023
Volum: 15
Hefte: 2
Sider: 491 - 535
Open Access

Importkilder

Scopus-ID: 2-s2.0-85137382892

Beskrivelse Beskrivelse

Tittel

Applying genetic technologies to combat infectious diseases in aquaculture

Sammendrag

isease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem. We argue that there is an urgent need to improve understanding of the genetic mechanisms involved, leading to the development of tools that can be applied to boost host resistance and reduce the disease burden. We draw on two pressing global disease problems as case studies—sea lice infestations in salmonids and white spot syndrome in shrimp. We review how the latest genetic technologies can be capitalised upon to determine the mechanisms underlying inter- and intra-species variation in pathogen/parasite resistance, and how the derived knowledge could be applied to boost disease resistance using selective breeding, gene editing and/or with targeted feed treatments and vaccines. Gene editing brings novel opportunities, but also implementation and dissemination challenges, and necessitates new protocols to integrate the technology into aquaculture breeding programmes. There is also an ongoing need to minimise risks of disease agents evolving to overcome genetic improvements to host resistance, and insights from epidemiological and evolutionary models of pathogen infestation in wild and cultured host populations are explored. Ethical issues around the different approaches for achieving genetic resistance are discussed. Application of genetic technologies and approaches has potential to improve fundamental knowledge of mechanisms affecting genetic resistance and provide effective pathways for implementation that could lead to more resistant aquaculture stocks, transforming global aquaculture.

Bidragsytere

Nicholas Andrew Robinson

  • Tilknyttet:
    Forfatter
    ved University of Melbourne
  • Tilknyttet:
    Forfatter
    ved Avl og genetikk ved NOFIMA

Diego Robledo

  • Tilknyttet:
    Forfatter
    ved The University of Edinburgh

Lene Sveen

  • Tilknyttet:
    Forfatter
    ved Fiskehelse ved NOFIMA

Rose Ruiz Daniels

  • Tilknyttet:
    Forfatter
    ved The University of Edinburgh

Aleksei Krasnov

  • Tilknyttet:
    Forfatter
    ved Fiskehelse ved NOFIMA
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