Seksuelle bivirkninger av antidepressive legemidler

Sexual dysfunction is often concurrent with depressive disorders. Antidepressants may induce or augment sexual dysfunction as an adverse effect. About 40% of all patients treated with selective serotonin reuptake inhibitors, or other serotonergic agents, report such effects. If sexual dysfunction is not adequately dealt with it may contribute to noncompliance and thus compromise treatment. For the norepinephrine and dopamine reuptake inhibitor bupropion, the incidence of sexual adverse effects is equal to that for placebo. Additional treatment with bupropion, or switching to mirtazapin or bupropion, may be effective. Studies in men have documented positive effects of concomitant treatment with sildenafil or tadalafil.