Cristin-resultat-ID: 851345
Sist endret: 21. januar 2015, 16:10
Resultat
Poster
2011

Reduced gastroesophageal reflux symptoms after weight loss in a large prospective population-based cohort study. The Nord-Trøndelag Health Study (the HUNT study)

Bidragsytere:
  • Eivind Ness-Jensen
  • Anna Lindam
  • Jesper Lagergren og
  • Kristian Hveem

Presentasjon

Navn på arrangementet: United European Gastroenterology Week 2011
Sted: Stockholm
Dato fra: 22. oktober 2011
Dato til: 26. oktober 2011

Arrangør:

Arrangørnavn: United European Gastroenterology Federation

Om resultatet

Poster
Publiseringsår: 2011

Beskrivelse Beskrivelse

Tittel

Reduced gastroesophageal reflux symptoms after weight loss in a large prospective population-based cohort study. The Nord-Trøndelag Health Study (the HUNT study)

Sammendrag

INTRODUCTION High body mass index (BMI) is an established risk factor for gastroesophageal reflux symptoms (GERS). However, it is not clear if weight loss reduces GERS. AIMS & METHODS The aim was to clarify the effect of weight loss on GERS in a large prospective population-based cohort study. The study was part of the Nord-Trøndelag Health Study (HUNT) conducted in Nord-Trøndelag County, Norway. All adult residents of the county were invited. In HUNT 2 (1995-1997) and HUNT 3 (2006-2009), 58869 (63%) and 44997 persons (48%) responded to a GERS questionnaire, respectively. Among these, a cohort of 29610 persons was prospectively followed from HUNT 2 through HUNT 3. RESULTS Among the 9299 persons with any GERS (minor or severe GERS) in HUNT 2, 2398 persons (26%) had no GERS in HUNT 3. Among the 1553 persons with severe GERS in HUNT 2, 1013 (65%) had no or minor GERS in HUNT 3. GERS was dose-dependently reduced by weight loss, except among those with severe GERS not using antireflux medication at least weekly. The effect of weight loss and antireflux medication seemed to be synergistic. All analyses were adjusted for sex, age, tobacco smoking, alcohol consumption, education, and physical exercise. CONCLUSION Weight loss reduced GERS dose-dependently in the general population. The effect of weight loss and antireflux medication seemed to be synergistic.

Bidragsytere

Aktiv cristin-person

Eivind Ness-Jensen

  • Tilknyttet:
    Forfatter
    ved Institutt for samfunnsmedisin og sykepleie ved Norges teknisk-naturvitenskapelige universitet
  • Tilknyttet:
    Forfatter
    ved Klinikk for medisin og rehabilitering ved Helse Nord-Trøndelag HF
  • Tilknyttet:
    Forfatter
    ved HUNT forskningssenter ved Norges teknisk-naturvitenskapelige universitet

Anna Lindam

  • Tilknyttet:
    Forfatter
    ved Karolinska Institutet

Jesper Lagergren

  • Tilknyttet:
    Forfatter
    ved King's College London
  • Tilknyttet:
    Forfatter
    ved Karolinska Institutet

Kristian Hveem

  • Tilknyttet:
    Forfatter
    ved Institutt for samfunnsmedisin og sykepleie ved Norges teknisk-naturvitenskapelige universitet
  • Tilknyttet:
    Forfatter
    ved HUNT forskningssenter ved Norges teknisk-naturvitenskapelige universitet
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