Cristin-resultat-ID: 1522615
Sist endret: 4. desember 2017, 23:49
Resultat
Vitenskapelig foredrag
2017

Hypoxia tolerance and responses to hypoxic stress during heart and skeletal muscle inflammation in Atlantic salmon (Salmo salar)

Bidragsytere:
  • Morten Lund
  • Maria Krudtaa Dahle
  • Gerrit Timmerhaus
  • Marta Alarcon
  • Mark Powell
  • Vidar Aspehaug
  • mfl.

Presentasjon

Navn på arrangementet: 18th International Conference on Diseases of Fish and Shellfish
Sted: Belfast
Dato fra: 6. september 2017
Dato til: 8. september 2017

Arrangør:

Arrangørnavn: European Association of Fish pathologists (EAFP)

Om resultatet

Vitenskapelig foredrag
Publiseringsår: 2017

Beskrivelse Beskrivelse

Tittel

Hypoxia tolerance and responses to hypoxic stress during heart and skeletal muscle inflammation in Atlantic salmon (Salmo salar)

Sammendrag

Introduction Heart and skeletal muscle inflammation (HSMI) is associated with Piscine orthoreovirus (PRV) infection and is an important disease in Atlantic salmon (Salmo salar) aquaculture. Since PRV infects erythrocytes, and farmed salmon frequently experience environmental hypoxia, effects of PRV infection and HSMI on hypoxia tolerance, cardiorespiratory performance and blood oxygen transport were studied. Methodology A cohabitation trial with PRV-infected fish was performed, and one group (PRV-H) was exposed to periodic hypoxic stress for 2h at 40% O2 at 4, 7 and 10 weeks post-infection (WPI). We analyzed the effects of PRV infection on individual incipient lethal oxygen saturation (ILOS) in an hypoxia challenge test (HCT). Maximum heart rate (fHmax), hemoglobin-levels and hemoglobin-oxygen affinity measurements were also performed. Results Periodic hypoxic stress did not influence the infection levels or histopathological changes in the heart. At 7 WPI (peak level of PRV infection) and 10 WPI (peak HSMI pathology) the PRV-infected group exhibited reduced hypoxia tolerance compared to non-infected fish. This was in line with maximum heart rate (fHmax) measurements at 10 WPI, showing a lower temperature optimum (Topt) for aerobic scope for PRV-infected fish, which may indicate reduced cardiac performance and thermal tolerance. Although the PRV-H group had reduced hemoglobin-oxygen affinity compared to non-infected fish, this group performed equal to non-infected fish in hypoxic stress tests and heart rate measurements at 10 WPI, suggesting a preconditioning effect of previous hypoxic stress. Conclusion Hypoxia tolerance and cardiac performance are impaired during HSMI. This effect can be improved by preconditioning from short-term hypoxic stress episodes.

Bidragsytere

Morten Lund

  • Tilknyttet:
    Forfatter
    ved Institutt for prekliniske fag og patologi ved Norges miljø- og biovitenskapelige universitet
Aktiv cristin-person

Maria Krudtå Dahle

Bidragsyterens navn vises på dette resultatet som Maria Krudtaa Dahle
  • Tilknyttet:
    Forfatter
    ved Forskningsgruppe fiskehelse ved Veterinærinstituttet

Gerrit Timmerhaus

  • Tilknyttet:
    Forfatter
    ved Gruppe for forskningsinfrastruktur ved Universitetet i Oslo

Marta Alarcon

  • Tilknyttet:
    Forfatter
    ved Harstad ved Veterinærinstituttet

Mark Darryn Powell

Bidragsyterens navn vises på dette resultatet som Mark Powell
  • Tilknyttet:
    Forfatter
    ved Institutt for biovitenskap (BIO) ved Universitetet i Bergen
1 - 5 av 8 | Neste | Siste »