Changing boundary conditons with operations in deeper water and arctic areas, more extreme climate, and increased demand for energy and food supply from the oceans give new environmental, safety, functional, geographic and structural challenges. Cutting-edge interdisciplinary research will provide the needed bridge to make sustainable autonomy a reality for ships and ocean structures, unmanned vehicles and marine operations, to meet the challenges related to greener and safer maritime transport, monitoring and surveillance of the seas and oceans, offshore renewable energy, and oil and gas exploration and production in deeper and Arctic waters. Ground-breaking research in autonomous marine operations and systems requires deep interdisciplinary research. The main knowledge fields of AMOS are marine hydrodynamics, structural mechanics, guidance, navigation and sensor systems, and control and optimization. Autonomous marine operations and systems requires that mathematical models of hydrodynamics and structural dynamics form the basis of the design, analysis and real-time operation of the automatic control and monitoring systems to account for structural flexibility and strong hydrodynamic non-linearities. In the application 8 research projects are presented. They will contribute to fill in the gap defined by 5 major research questions raised in the proposal for the first 5 years. AMOS will organize its research activities in a number of targeted research projects with well defined objectives, tasks and outcomes, to be executed in three phases - 3, 5 and 10 years perspective. AMOS will annually evaluate the different projects and redirect the research dynamically based on the findings and advises received from the scientific advisory board, user reference groups, and at internal and external workshops. Norwegian version Forskere ved AMOS vil jobbe mellom fagdisiplinene for å etablere et verdensledende forskningssenter på autonome marine operasjoner og systemer. AMOS vil bidra med fundamental og interdisiplinær kunnskap i hydrodynamikk, marine konstruksjoner, reguleringsteknikk og autonomitet. Forskningsresultatene vil bli brukt til å utvikle intelligente skip og havkonstruksjoner, autonome ubemannede fartøy (under, på og over vann) og roboter for høy presisjon og sikkerhetskritiske operasjoner i ekstreme områder. Dette er nødvendig for å møte utfordringene relatert til miljø og klima, sikker maritim transport, kartlegging og overvåkning av kystområdene, offshore fornybar energi, fiskeri og havbruk samt Arktisk olje- og gassutvinning på dypt vann.